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  1. Cardiovascular disease complications are the leading cause of morbidity and mortality in patients with Type 2 diabetes (T2DM). Left ventricular diastolic dysfunction (LVDD) is one of the earliest myocardial ch...

    Authors: Yu Rong, Wei Liu, Ke Li, Jian Guo and Xue-Ping Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:159
    Content type: Research Published on:

  2. Ankylosing spondylitis (AS) is a chronic inflammatory disease associated with an increased risk of metabolic syndrome (MetS), a cluster of cardiometabolic risk factors. However, the prevalence of MetS in AS re...

    Authors: Sandeep Samethadka Nayak, Kwame Boateng Agyeman, Khushbu Viresh Janani, Maryam Jafari, Mohammad Amouzadeh Lichahi, Pubali Biswas, Mohammad Hashemi, Nimra Shafi, Yasmin Sahli, Ehsan Amini-Salehi and Narsimha Rao Keetha
    Citation: Diabetology & Metabolic Syndrome 2025 17:158
    Content type: Review Published on:

  3. The aim of this study was to evaluate and compare the usefulness of the C-reactive protein (CRP)-triglyceride glucose (TyG) index (CTI) and other insulin resistance (IR) or inflammatory indexes for predicting ...

    Authors: Ang Gao, Bo Peng, Yanan Gao, Zhiqiang Yang, Zhifan Li, Tingting Guo, Hong Qiu and Runlin Gao
    Citation: Diabetology & Metabolic Syndrome 2025 17:157
    Content type: Research Published on:

  4. In 2021, IDegLira was introduced in China as a treatment option for patients with type 2 diabetes mellitus (T2DM). We aimed to evaluate the long-term cost-utility of IDegLira compared to basal-bolus therapy an...

    Authors: Junling Weng, Dunming Xiao and Yingyao Chen
    Citation: Diabetology & Metabolic Syndrome 2025 17:156
    Content type: Research Published on:

  6. Diabetic nephropathy (DN) is one of the most common and serious microvascular complications of diabetes mellitus (DM) and is the main cause of end-stage renal disease. Endothelial dysfunction caused by persist...

    Authors: Zeng Wu, Yu Gao, Chun-yue Zuo, Xiao-rong Wang, Xiao-han Chen, Xiao-hong Zhou and Wei-juan Gao
    Citation: Diabetology & Metabolic Syndrome 2025 17:154
    Content type: Review Published on:

  7. Non-alcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated steatotic liver disease (MASLD) are common chronic liver diseases worldwide, both of which are closely associated with an increase...

    Authors: Jialu Lv, Jiangnan Yao, Leyi Zheng, Jiaxin Shao, Jijie Jin, Qianrong Zheng, Jiayi Teng, Jianghua Zhou, Fuman Cai, Pan Huang and Xuepei Jiang
    Citation: Diabetology & Metabolic Syndrome 2025 17:153
    Content type: Research Published on:

  8. Low-fat diets have gained considerable attention in the management of obesity. The present meta-analysis evaluated randomized controlled trials (RCTs) to determine whether adults adhering to low-fat diets (≤ 3...

    Authors: Sepideh Soltani, Fatemeh Meshkini, Kimia Torabinasab, Elham Razmpoosh, Omid Toupchian, Sheida Zeraattalab-Motlagh, Amirhossein Hemmati, Zohreh Sadat Sangsefidi and Shima Abdollahi
    Citation: Diabetology & Metabolic Syndrome 2025 17:152
    Content type: Review Published on:

  9. The risk of bleeding associated with antiplatelet therapy in patients with coronary artery disease (CAD) has received a lot of attention. The aim of this study was to investigate the relationship between ABO b...

    Authors: Menglu Liu, Jiawen Li, Kailun Yan, Kexin Zhang, Pei Zhu, Xiaofang Tang, Deshan Yuan, Yuejin Yang, Runlin Gao, Jinqing Yuan and Xueyan Zhao
    Citation: Diabetology & Metabolic Syndrome 2025 17:151
    Content type: Research Published on:

  10. This correspondence marks the 10-year milestone of InsulinAPP, a Brazilian-developed electronic glycemic management system (eGMS) designed to support inpatient insulin therapy. Initially published in 2015, Ins...

    Authors: Marcos Tadashi Kakitani Toyoshima, Julia Mandaro Lavinas-Jones, Alina Coutinho Rodrigues Feitosa and Marcia Nery
    Citation: Diabetology & Metabolic Syndrome 2025 17:150
    Content type: Correspondence Published on:

  11. This expert consensus provides a standardized methodology for interpreting continuous glucose monitoring (CGM) data to optimize diabetes management. It aims to help healthcare professionals recognize glycemic ...

    Authors: Luis Eduardo Calliari, Álvaro Contreras Sepúlveda, Nicolás Coronel-Restrepo, Laura Kabakian, Rodrigo N. Lamounier, Emma Picasso, Adrian Proietti, Alex Ramírez-Rincón and Alicia E. Yépez-Rodriguez
    Citation: Diabetology & Metabolic Syndrome 2025 17:149
    Content type: Review Published on:

  12. The α-klotho is crucial in diabetes and its related complications. This study seeks to explore the link between α-klotho levels and the risk of diabetic kidney disease (DKD) as well as all-cause and cardiovasc...

    Authors: Yi Kang, Qian Jin, Mengqi Zhou, Huijuan Zheng, Danwen Li, Jingwei Zhou, Jie Lv and Yaoxian Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:148
    Content type: Research Published on:

  13. Gestational diabetes mellitus (GDM) is a common pregnancy complication with far-reaching implications for maternal and offspring health, strongly tied to epigenetic modifications, particularly DNA methylation....

    Authors: Na Wang, Suping Li and Li Yang
    Citation: Diabetology & Metabolic Syndrome 2025 17:147
    Content type: Research Published on:

  14. Previous studies of acupuncture for type 2 diabetes mellitus (T2DM) have focused on lowering blood glucose and improving symptoms; however, the mechanisms underlying these effects have not been systematically ...

    Authors: Fang Luo, Zhijun Ma, Hanhan Chen, Zhuoxuan Li, Junjie Feng, Chengguo Su and Jun Zhu
    Citation: Diabetology & Metabolic Syndrome 2025 17:146
    Content type: Review Published on:

  15. The treatment and prevention of diabetic retinopathy (DR) remain significant challenges. Mendelian randomization (MR) has been widely used to explore novel therapeutic targets. In this study, we conducted a sy...

    Authors: Long Xie, Yu Qin Peng and Xiang Shen
    Citation: Diabetology & Metabolic Syndrome 2025 17:145
    Content type: Research Published on:

  16. Insulin secretion and resistance are key pathophysiological factors in type 2 diabetes. However, only 55% of patients achieve long-term blood glucose treatment goals, highlighting the need to clarify the patho...

    Authors: Masahiro Ohira, Naoyuki Kawagoe, Chisato Kameyama, Yuko Kondou, Madoka Igarashi and Hajime Ueshiba
    Citation: Diabetology & Metabolic Syndrome 2025 17:144
    Content type: Research Published on:

  17. Metabolic syndrome (MetS) is a conglomerate of metabolic abnormalities including hypertension, obesity, hyperglycemia, hypertriglyceridemia, and low levels of high-density lipoprotein cholesterol (HDL-C). The ...

    Authors: Danyang Zhang, Haitao Shi, Chongcao Wei, Fenrong Chen, Pan Zhang, Xin Gao and Yan Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:143
    Content type: Research Published on:

  18. Among noncommunicable diseases, cardiovascular disease (CVD) is the leading cause of mortality and morbidity. In China, diabetes is renowned for its high incidence rate, and the body roundness index (BRI) is a...

    Authors: Youli Kong, Qian Luo, Qing Zhang and Quan Wei
    Citation: Diabetology & Metabolic Syndrome 2025 17:142
    Content type: Research Published on:

  19. Some observational studies found that there is an epidemiological association between type 2 diabetes (T2D) and sleep apnea (SA) and glucose-lowering drugs may lower SA risk. However, the causative relationshi...

    Authors: Fang Cheng, Kang Yang, Yaoling Wang, Fan Yang, Xinyu Niu and Wei Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:141
    Content type: Research Published on:

  20. The global prevalence of diabetes has been steadily increasing, with a growing number of younger individuals being affected. Over recent decades, various antidiabetic drugs have been repurposed for treating co...

    Authors: Yuqi Li, Tao Zhou, Zhiyu Liu, Xinyao Zhu, Qilong Wu, Chunyang Meng and Qingfu Deng
    Citation: Diabetology & Metabolic Syndrome 2025 17:140
    Content type: Research Published on:

  21. This study explores the causal relationships between five major lipids, 249 circulating metabolites, and four diabetic retinopathy (DR) outcomes: overall DR, background DR, severe background DR, and proliferat...

    Authors: Jiawei Wang, Jing Su, Danyan Liu and Jingxue Ma
    Citation: Diabetology & Metabolic Syndrome 2025 17:139
    Content type: Research Published on:

  22. We aimed to probe the effect of microRNA (miR)-455-3p derived from human umbilical cord mesenchymal stem cell exosomes (hucMSCs-Exos) in targeting calcium/calmodulin-dependent protein kinase 2 inhibitor 1 (CAM...

    Authors: Yan Zhang, Mingyu Du, Baosheng Zhu, Runmei Ma and Jinman Zhang
    Citation: Diabetology & Metabolic Syndrome 2025 17:138
    Content type: Research Published on:

  23. The Fasting Mimicking Diet (FMD) has gained significant attention as a potential intervention for reducing cardiovascular risk factors. While studies have investigated its effectiveness, findings have been inc...

    Authors: Milad Mohammadzadeh, Mahdi Amirpour, Hamid Ahmadirad, Fatemeh Abdi, Saman Khalesi, Niayesh Naghshi, Alireza Bahrami and Ehsan Hejazi
    Citation: Diabetology & Metabolic Syndrome 2025 17:137
    Content type: Review Published on:

  24. Social determinants of health (SDOH) and metabolic syndrome (MetS) are related, but their combined effect on mortality risk remains unclear.

    Authors: Xiaohan Ma, Sheng Chen, Lin Guo, Shuaikang Wang, Junchao Wu, Lingling Wu, Ting Zhang, Hongjun Gao and Encun Hou
    Citation: Diabetology & Metabolic Syndrome 2025 17:136
    Content type: Research Published on:

  25. Authors: Vanessa Estato, Nathalie Obadia, Paulo Henrique Chateaubriand, Vivian Figueiredo, Marcela Curty, Mariana Costa Silva, Renata Gabriela Lustosa Ferreira, Juliane Santa-Ritta, Marcela Campos Baroni, Alessandra Aragão, João Oliveira Góes Neno, Clara Avelar Mendes Vasconcellos, Joana Costa D’Avila, Marcelo Gomes Granja and Hugo Caire de Castro Faria-Neto
    Citation: Diabetology & Metabolic Syndrome 2025 17:135
    Content type: Correction Published on:

    The original article was published in Diabetology & Metabolic Syndrome 2025 17:2

  26. Authors: Sichun Wen, Jingfen Li, Zheng Xie, Xiaohui Chen, Junyi Li and Xiayi Lin
    Citation: Diabetology & Metabolic Syndrome 2025 17:134
    Content type: Correction Published on:

    The original article was published in Diabetology & Metabolic Syndrome 2025 17:67

  27. The effect of insulin resistance (IR) on epicardial adipose tissue (EAT) remains uncertain. This study aimed to investigate how early-stage IR influences EAT, contributing to myocardial fibrosis and left ventr...

    Authors: Runze Zhu, Wenxian Wang, Yan Gao, Jian Wang, Bowen Li, Zhenyu Cheng, Congshan Ji, Hui Gu, Xianshun Yuan, Shifeng Yang and Ximing Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:133
    Content type: Research Published on:

  28. To evaluate the effect of impaired fasting glucose (IFG) and various anti-diabetic agents on the risk of incident major cardiovascular events (MACE) in patients with inflammatory arthritis (IA) including rheum...

    Authors: Huan Meng, Ho So, Steven H. Lam and Lai-Shan Tam
    Citation: Diabetology & Metabolic Syndrome 2025 17:132
    Content type: Research Published on:

  29. Cardiovascular disease (CVD) remains a major global health challenge, particularly affected by glucose metabolism status. However, the relationship between estimated glucose disposal rate (eGDR) and future CVD...

    Authors: Xiaomin Liang, Kai Lai, Xiaohong Li, Di Ren, Shuiqing Gui, Zemao Xing and Ying Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:131
    Content type: Research Published on:

  30. The prognostic value of Magnesium Depletion Score (MDS) in Diabetic Kidney Disease (DKD) patients is still unclear. This study aimed to determine the associations between MDS and long-term mortality in DKD pop...

    Authors: Lingzhi Xing, Yubowen Gong, GuoJia Liao, Liying Wang and Ling Chen
    Citation: Diabetology & Metabolic Syndrome 2025 17:130
    Content type: Research Published on:

  31. The purpose of this study is to investigate the relationship between the weight-adjusted waist index (WWI) and the incidence of carotid atherosclerotic plaque in patients with type 2 diabetes (T2DM) in the Chi...

    Authors: Yu Qin, Jing-Jing Ye, Xu-Nan Wu, Yue Xia, Hao-Xiang Li, Ling Yang, Xia Deng and Guo-Yue Yuan
    Citation: Diabetology & Metabolic Syndrome 2025 17:129
    Content type: Research Published on:

  33. Circulating immune cells reportedly affect diabetic neuropathy (DN). Although associations have been previously established between numerous biomarkers and diseases, elucidating their causal relationships rema...

    Authors: Lingfen Ji, Puyu Li, Nana Duan, Jinjin Xu, Yijuan Song, Bohui Shu, Lijun Liang and Fuli Zhao
    Citation: Diabetology & Metabolic Syndrome 2025 17:127
    Content type: Research Published on:

  34. To compare the effects of switching from dipeptidyl peptidase 4 (DPP-4) inhibitors to oral semaglutide on oxidative stress and glucose variability assessed by continuous glucose monitoring in patients with typ...

    Authors: Makoto Ohara, Hiroki Yokoyama, Hiroaki Seino, Tomoki Fujikawa, Yo Kohata, Noriyuki Takahashi, Shunichiro Irie, Michishige Terasaki, Yusaku Mori, Tomoyasu Fukui and Sho-ichi Yamagishi
    Citation: Diabetology & Metabolic Syndrome 2025 17:126
    Content type: Research Published on:

  35. Chronic low-grade inflammation and dyslipidemia are central to the development of insulin resistance (IR) and type 2 diabetes (T2D). The ratio of high-sensitivity C-reactive protein (hs-CRP) to high-density li...

    Authors: Kun Xue, Meijun Sun, Chao Zong, Shanshan Xing and Hang Xue
    Citation: Diabetology & Metabolic Syndrome 2025 17:125
    Content type: Research Published on:

  36. The global prevalence of diabetes is on an upward trajectory. The management of complications related to the condition has seen limited progress in recent years. Klotho, characterized as an anti-aging protein ...

    Authors: Kangxiang Wu, Jiaqi Chen, Yiying Lin and Jie Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:124
    Content type: Research Published on:

  37. Stroke due to large artery atherosclerosis (LAA-stroke) has a poor early prognosis despite appropriate medical treatment. Recently, various parameters reflecting pathological conditions such as insulin resista...

    Authors: Ki-Woong Nam, Hyung-Min Kwon and Yong-Seok Lee
    Citation: Diabetology & Metabolic Syndrome 2025 17:123
    Content type: Research Published on:

  38. The rising prevalence and high mortality of diabetes have made it a significant public health concern. This study explores how electroacupuncture (EA) influences the PI3K/Akt pathway and its role in regulating...

    Authors: Shaoyang Liu, Shuting Zhuang, Rui Li and Haoru Duan
    Citation: Diabetology & Metabolic Syndrome 2025 17:122
    Content type: Research Published on:

  39. Statins, a kind of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, are first-line cholesterol-lowering drugs that are widely used in the primary and secondary prevention of coronary ather...

    Authors: Hui Wang, Mulalibieke Heizhati, Nanfang Li, Lin Gan, Ling Yao, Mei Li, Li Cai, Xiufang Li, Xiayire Aierken, Dan Yu, Miaomiao Liu, Adalaiti Maitituersun, Qiaolifanayi Nuermaimaiti, Aketilieke Nusufujiang and Jing Hong
    Citation: Diabetology & Metabolic Syndrome 2025 17:121
    Content type: Research Published on:

  40. Overweight and obesity have been associated with an altered intestinal microbiome. Recent investigations have demonstrated that fiber supplementation, including chitosan, can exert beneficial and protective ef...

    Authors: Somaye Fatahi, Mohammad Hassan Sohouli, Koroush Vahidshahi, Pejman Rohani, Majid Safa, Masoud Salehi, Mihnea-Alexandru Găman and Farzad Shidfar
    Citation: Diabetology & Metabolic Syndrome 2025 17:120
    Content type: Research Published on:

  41. Obesity is a chronic and complex disease influenced by various factors that hinder weight loss and maintenance. However, perceptions of obesity are often marked by stigma. This study assessed perceptions of ob...

    Authors: Luiz F. Viola, Fabiana Mandel, Cynthia M. Valerio, Maria Augusta Bernardini and Bruno Halpern
    Citation: Diabetology & Metabolic Syndrome 2025 17:119
    Content type: Research Published on:

  42. Metabolic syndrome (MetS) is increasingly viewed as a pressing concern for public health globally. The objective of this study was to compare the predictive ability of 17 anthropometric indices for the risk of...

    Authors: Peizhen Zhou, Wei Liu, Kangning Sun, Zekun Zhao, Wenqian Zhu, Jing Zhang and Wenjun Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:118
    Content type: Research Published on:

  43. Most existing studies have primarily focused on the effects of Traditional Chinese Exercises (TCEs) on glycemic control in individuals with prediabetes, while specific recommendations for managing dyslipidemia...

    Authors: Ruixiang Yan, Wuwen Peng, Di Lu, Jiaxin He, Jian Sun, Lingju Guan, Shufang Liu and Duanying Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:117
    Content type: Review Published on:

  45. Type 2 diabetes mellitus (T2DM) is known to worsen the prognosis of heart failure (HF), but its specific impact on patients with ischemic versus non-ischemic heart failure with mildly reduced ejection fraction...

    Authors: Zhican Liu, Hailong Hu, Jianping Zeng and Mingyan Jiang
    Citation: Diabetology & Metabolic Syndrome 2025 17:115
    Content type: Research Published on:

  46. Type 2 diabetes mellitus (T2DM) is a kind of metabolic disease characterized by aberrant insulin secretion as a result of -cell loss or injury, or by impaired insulin sensitivity of peripheral tissues, which f...

    Authors: Mengjuan Wei, Yan Wang, Yufei Zhang and Yun Qiao
    Citation: Diabetology & Metabolic Syndrome 2025 17:114
    Content type: Comment Published on:

  47. Both type 1 and type 2 diabetes mellitus (T1D and T2D) are associated with poor bone health and an increased risk of fracture in adults. However, there are limited data regarding the effects of diabetes on the...

    Authors: Sowmya Krishnan, Christopher E. Aston, Jennifer Chadwick, Shelly Gulati, Huaiwen Wang, Susan B. Sisson, Madhusmita Misra and Steven D. Chernausek
    Citation: Diabetology & Metabolic Syndrome 2025 17:113
    Content type: Research Published on:

  48. Stress hyperglycemia ratio (SHR) has been associated with increased mortality from various cerebrovascular events and a higher incidence of acute kidney injury (AKI) in certain patient populations. However, th...

    Authors: Yue Shi, Hangyu Duan, Jing Liu, Xiujie Shi, Mingming Zhao and Yu Zhang
    Citation: Diabetology & Metabolic Syndrome 2025 17:112
    Content type: Research Published on:

  49. To date, no meta-analysis has reported on the role of transdermal estrogens combined with Medroxyprogesterone Acetate (MPA) in relation to cardiovascular disease (CVD) risk factors in postmenopausal women. To ...

    Authors: Fan Zhou, Kousalya Prabahar and Jiao Shu
    Citation: Diabetology & Metabolic Syndrome 2025 17:111
    Content type: Review Published on:

  50. Considering the important role of cardiometabolic risk factors in different societies on increasing the burden of non-communicable diseases, in this study we will investigate the possible effects of Beinagluti...

    Authors: Yan Xu, Periyannan Velu, Li Hu and Nathalia Sernizon Guimarães
    Citation: Diabetology & Metabolic Syndrome 2025 17:110
    Content type: Research Published on:

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Diabetology & Metabolic Syndrome

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