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Page 4 of 51

  1. Insulin secretion and resistance are key pathophysiological factors in type 2 diabetes. However, only 55% of patients achieve long-term blood glucose treatment goals, highlighting the need to clarify the patho...

    Authors: Masahiro Ohira, Naoyuki Kawagoe, Chisato Kameyama, Yuko Kondou, Madoka Igarashi and Hajime Ueshiba
    Citation: Diabetology & Metabolic Syndrome 2025 17:144
    Content type: Research Published on:

  2. Metabolic syndrome (MetS) is a conglomerate of metabolic abnormalities including hypertension, obesity, hyperglycemia, hypertriglyceridemia, and low levels of high-density lipoprotein cholesterol (HDL-C). The ...

    Authors: Danyang Zhang, Haitao Shi, Chongcao Wei, Fenrong Chen, Pan Zhang, Xin Gao and Yan Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:143
    Content type: Research Published on:

  3. Among noncommunicable diseases, cardiovascular disease (CVD) is the leading cause of mortality and morbidity. In China, diabetes is renowned for its high incidence rate, and the body roundness index (BRI) is a...

    Authors: Youli Kong, Qian Luo, Qing Zhang and Quan Wei
    Citation: Diabetology & Metabolic Syndrome 2025 17:142
    Content type: Research Published on:

  4. Some observational studies found that there is an epidemiological association between type 2 diabetes (T2D) and sleep apnea (SA) and glucose-lowering drugs may lower SA risk. However, the causative relationshi...

    Authors: Fang Cheng, Kang Yang, Yaoling Wang, Fan Yang, Xinyu Niu and Wei Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:141
    Content type: Research Published on:

  5. This study explores the causal relationships between five major lipids, 249 circulating metabolites, and four diabetic retinopathy (DR) outcomes: overall DR, background DR, severe background DR, and proliferat...

    Authors: Jiawei Wang, Jing Su, Danyan Liu and Jingxue Ma
    Citation: Diabetology & Metabolic Syndrome 2025 17:139
    Content type: Research Published on:

  6. We aimed to probe the effect of microRNA (miR)-455-3p derived from human umbilical cord mesenchymal stem cell exosomes (hucMSCs-Exos) in targeting calcium/calmodulin-dependent protein kinase 2 inhibitor 1 (CAM...

    Authors: Yan Zhang, Mingyu Du, Baosheng Zhu, Runmei Ma and Jinman Zhang
    Citation: Diabetology & Metabolic Syndrome 2025 17:138
    Content type: Research Published on:

  7. The Fasting Mimicking Diet (FMD) has gained significant attention as a potential intervention for reducing cardiovascular risk factors. While studies have investigated its effectiveness, findings have been inc...

    Authors: Milad Mohammadzadeh, Mahdi Amirpour, Hamid Ahmadirad, Fatemeh Abdi, Saman Khalesi, Niayesh Naghshi, Alireza Bahrami and Ehsan Hejazi
    Citation: Diabetology & Metabolic Syndrome 2025 17:137
    Content type: Review Published on:

  8. Social determinants of health (SDOH) and metabolic syndrome (MetS) are related, but their combined effect on mortality risk remains unclear.

    Authors: Xiaohan Ma, Sheng Chen, Lin Guo, Shuaikang Wang, Junchao Wu, Lingling Wu, Ting Zhang, Hongjun Gao and Encun Hou
    Citation: Diabetology & Metabolic Syndrome 2025 17:136
    Content type: Research Published on:

  9. Authors: Vanessa Estato, Nathalie Obadia, Paulo Henrique Chateaubriand, Vivian Figueiredo, Marcela Curty, Mariana Costa Silva, Renata Gabriela Lustosa Ferreira, Juliane Santa-Ritta, Marcela Campos Baroni, Alessandra Aragão, João Oliveira Góes Neno, Clara Avelar Mendes Vasconcellos, Joana Costa D’Avila, Marcelo Gomes Granja and Hugo Caire de Castro Faria-Neto
    Citation: Diabetology & Metabolic Syndrome 2025 17:135
    Content type: Correction Published on:

    The original article was published in Diabetology & Metabolic Syndrome 2025 17:2

  10. Authors: Sichun Wen, Jingfen Li, Zheng Xie, Xiaohui Chen, Junyi Li and Xiayi Lin
    Citation: Diabetology & Metabolic Syndrome 2025 17:134
    Content type: Correction Published on:

    The original article was published in Diabetology & Metabolic Syndrome 2025 17:67

  11. The effect of insulin resistance (IR) on epicardial adipose tissue (EAT) remains uncertain. This study aimed to investigate how early-stage IR influences EAT, contributing to myocardial fibrosis and left ventr...

    Authors: Runze Zhu, Wenxian Wang, Yan Gao, Jian Wang, Bowen Li, Zhenyu Cheng, Congshan Ji, Hui Gu, Xianshun Yuan, Shifeng Yang and Ximing Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:133
    Content type: Research Published on:

  12. To evaluate the effect of impaired fasting glucose (IFG) and various anti-diabetic agents on the risk of incident major cardiovascular events (MACE) in patients with inflammatory arthritis (IA) including rheum...

    Authors: Huan Meng, Ho So, Steven H. Lam and Lai-Shan Tam
    Citation: Diabetology & Metabolic Syndrome 2025 17:132
    Content type: Research Published on:

  13. Cardiovascular disease (CVD) remains a major global health challenge, particularly affected by glucose metabolism status. However, the relationship between estimated glucose disposal rate (eGDR) and future CVD...

    Authors: Xiaomin Liang, Kai Lai, Xiaohong Li, Di Ren, Shuiqing Gui, Zemao Xing and Ying Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:131
    Content type: Research Published on:

  14. The prognostic value of Magnesium Depletion Score (MDS) in Diabetic Kidney Disease (DKD) patients is still unclear. This study aimed to determine the associations between MDS and long-term mortality in DKD pop...

    Authors: Lingzhi Xing, Yubowen Gong, GuoJia Liao, Liying Wang and Ling Chen
    Citation: Diabetology & Metabolic Syndrome 2025 17:130
    Content type: Research Published on:

  15. The purpose of this study is to investigate the relationship between the weight-adjusted waist index (WWI) and the incidence of carotid atherosclerotic plaque in patients with type 2 diabetes (T2DM) in the Chi...

    Authors: Yu Qin, Jing-Jing Ye, Xu-Nan Wu, Yue Xia, Hao-Xiang Li, Ling Yang, Xia Deng and Guo-Yue Yuan
    Citation: Diabetology & Metabolic Syndrome 2025 17:129
    Content type: Research Published on:

  17. Circulating immune cells reportedly affect diabetic neuropathy (DN). Although associations have been previously established between numerous biomarkers and diseases, elucidating their causal relationships rema...

    Authors: Lingfen Ji, Puyu Li, Nana Duan, Jinjin Xu, Yijuan Song, Bohui Shu, Lijun Liang and Fuli Zhao
    Citation: Diabetology & Metabolic Syndrome 2025 17:127
    Content type: Research Published on:

  18. To compare the effects of switching from dipeptidyl peptidase 4 (DPP-4) inhibitors to oral semaglutide on oxidative stress and glucose variability assessed by continuous glucose monitoring in patients with typ...

    Authors: Makoto Ohara, Hiroki Yokoyama, Hiroaki Seino, Tomoki Fujikawa, Yo Kohata, Noriyuki Takahashi, Shunichiro Irie, Michishige Terasaki, Yusaku Mori, Tomoyasu Fukui and Sho-ichi Yamagishi
    Citation: Diabetology & Metabolic Syndrome 2025 17:126
    Content type: Research Published on:

  19. Chronic low-grade inflammation and dyslipidemia are central to the development of insulin resistance (IR) and type 2 diabetes (T2D). The ratio of high-sensitivity C-reactive protein (hs-CRP) to high-density li...

    Authors: Kun Xue, Meijun Sun, Chao Zong, Shanshan Xing and Hang Xue
    Citation: Diabetology & Metabolic Syndrome 2025 17:125
    Content type: Research Published on:

  20. The global prevalence of diabetes is on an upward trajectory. The management of complications related to the condition has seen limited progress in recent years. Klotho, characterized as an anti-aging protein ...

    Authors: Kangxiang Wu, Jiaqi Chen, Yiying Lin and Jie Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:124
    Content type: Research Published on:

  21. Stroke due to large artery atherosclerosis (LAA-stroke) has a poor early prognosis despite appropriate medical treatment. Recently, various parameters reflecting pathological conditions such as insulin resista...

    Authors: Ki-Woong Nam, Hyung-Min Kwon and Yong-Seok Lee
    Citation: Diabetology & Metabolic Syndrome 2025 17:123
    Content type: Research Published on:

  22. The rising prevalence and high mortality of diabetes have made it a significant public health concern. This study explores how electroacupuncture (EA) influences the PI3K/Akt pathway and its role in regulating...

    Authors: Shaoyang Liu, Shuting Zhuang, Rui Li and Haoru Duan
    Citation: Diabetology & Metabolic Syndrome 2025 17:122
    Content type: Research Published on:

  23. Statins, a kind of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, are first-line cholesterol-lowering drugs that are widely used in the primary and secondary prevention of coronary ather...

    Authors: Hui Wang, Mulalibieke Heizhati, Nanfang Li, Lin Gan, Ling Yao, Mei Li, Li Cai, Xiufang Li, Xiayire Aierken, Dan Yu, Miaomiao Liu, Adalaiti Maitituersun, Qiaolifanayi Nuermaimaiti, Aketilieke Nusufujiang and Jing Hong
    Citation: Diabetology & Metabolic Syndrome 2025 17:121
    Content type: Research Published on:

  24. Overweight and obesity have been associated with an altered intestinal microbiome. Recent investigations have demonstrated that fiber supplementation, including chitosan, can exert beneficial and protective ef...

    Authors: Somaye Fatahi, Mohammad Hassan Sohouli, Koroush Vahidshahi, Pejman Rohani, Majid Safa, Masoud Salehi, Mihnea-Alexandru Găman and Farzad Shidfar
    Citation: Diabetology & Metabolic Syndrome 2025 17:120
    Content type: Research Published on:

  25. Obesity is a chronic and complex disease influenced by various factors that hinder weight loss and maintenance. However, perceptions of obesity are often marked by stigma. This study assessed perceptions of ob...

    Authors: Luiz F. Viola, Fabiana Mandel, Cynthia M. Valerio, Maria Augusta Bernardini and Bruno Halpern
    Citation: Diabetology & Metabolic Syndrome 2025 17:119
    Content type: Research Published on:

  26. Metabolic syndrome (MetS) is increasingly viewed as a pressing concern for public health globally. The objective of this study was to compare the predictive ability of 17 anthropometric indices for the risk of...

    Authors: Peizhen Zhou, Wei Liu, Kangning Sun, Zekun Zhao, Wenqian Zhu, Jing Zhang and Wenjun Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:118
    Content type: Research Published on:

  27. Most existing studies have primarily focused on the effects of Traditional Chinese Exercises (TCEs) on glycemic control in individuals with prediabetes, while specific recommendations for managing dyslipidemia...

    Authors: Ruixiang Yan, Wuwen Peng, Di Lu, Jiaxin He, Jian Sun, Lingju Guan, Shufang Liu and Duanying Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:117
    Content type: Review Published on:

  29. Type 2 diabetes mellitus (T2DM) is known to worsen the prognosis of heart failure (HF), but its specific impact on patients with ischemic versus non-ischemic heart failure with mildly reduced ejection fraction...

    Authors: Zhican Liu, Hailong Hu, Jianping Zeng and Mingyan Jiang
    Citation: Diabetology & Metabolic Syndrome 2025 17:115
    Content type: Research Published on:

  30. Type 2 diabetes mellitus (T2DM) is a kind of metabolic disease characterized by aberrant insulin secretion as a result of -cell loss or injury, or by impaired insulin sensitivity of peripheral tissues, which f...

    Authors: Mengjuan Wei, Yan Wang, Yufei Zhang and Yun Qiao
    Citation: Diabetology & Metabolic Syndrome 2025 17:114
    Content type: Comment Published on:

  31. Both type 1 and type 2 diabetes mellitus (T1D and T2D) are associated with poor bone health and an increased risk of fracture in adults. However, there are limited data regarding the effects of diabetes on the...

    Authors: Sowmya Krishnan, Christopher E. Aston, Jennifer Chadwick, Shelly Gulati, Huaiwen Wang, Susan B. Sisson, Madhusmita Misra and Steven D. Chernausek
    Citation: Diabetology & Metabolic Syndrome 2025 17:113
    Content type: Research Published on:

  32. Stress hyperglycemia ratio (SHR) has been associated with increased mortality from various cerebrovascular events and a higher incidence of acute kidney injury (AKI) in certain patient populations. However, th...

    Authors: Yue Shi, Hangyu Duan, Jing Liu, Xiujie Shi, Mingming Zhao and Yu Zhang
    Citation: Diabetology & Metabolic Syndrome 2025 17:112
    Content type: Research Published on:

  33. To date, no meta-analysis has reported on the role of transdermal estrogens combined with Medroxyprogesterone Acetate (MPA) in relation to cardiovascular disease (CVD) risk factors in postmenopausal women. To ...

    Authors: Fan Zhou, Kousalya Prabahar and Jiao Shu
    Citation: Diabetology & Metabolic Syndrome 2025 17:111
    Content type: Review Published on:

  34. Considering the important role of cardiometabolic risk factors in different societies on increasing the burden of non-communicable diseases, in this study we will investigate the possible effects of Beinagluti...

    Authors: Yan Xu, Periyannan Velu, Li Hu and Nathalia Sernizon Guimarães
    Citation: Diabetology & Metabolic Syndrome 2025 17:110
    Content type: Research Published on:

  35. The Cardiovascular-kidney-metabolic (CKM) syndrome is a health disorder caused by interactions between cardiovascular disease, kidney disease, and metabolism-related risk factors. The stress hyperglycemia rati...

    Authors: Fan-Shun Guo, Jia-Hao Dou, Jun-Xiang Wang, Chen Guo, Rui-Yun Wu, Xue-Lu Sun, Yi-Wei Hu and Jin Wei
    Citation: Diabetology & Metabolic Syndrome 2025 17:109
    Content type: Research Published on:

  36. Type 2 diabetes mellitus (T2DM) is closely associated with both environmental and genetic factors, involving multi-gene inheritance. This study examined the association between the polymorphic locus rs10757278...

    Authors: Xinyi Li, Aige Yang, Xiao Liu, Rui Zhang, Huimin Zhou and Shunjiang Xu
    Citation: Diabetology & Metabolic Syndrome 2025 17:108
    Content type: Research Published on:

  37. Fatty pancreas disease (FPD) is characterized by abnormal fat accumulation in pancreatic tissue and is often associated with obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM). While its pathophy...

    Authors: Tahsin Taner Karaevren, Refika Yorulmaz, Mahinur Cerit, Halit Nahit Şendur, Burak Kalafat, Gizem Yaz Aydın, Özlem Gülbahar, Mehmet Muhittin Yalçın, Ayhan Karakoç, Müjde Aktürk, Füsun Baloş Törüner, Alev Eroğlu Altınova, Taha Enes Çetin and Ethem Turgay Cerit
    Citation: Diabetology & Metabolic Syndrome 2025 17:107
    Content type: Research Published on:

  38. To assess the association between serum uric acid (SUA) level and the prevalence of diabetic retinopathy (DR) and chronic kidney disease (CKD) in patients with long-term diabetes.

    Authors: Hanying Wang, Liping Gu, Yuhang Ma, Xindan Xing, Yuan Qu, Xin Shi, Xinyi Liu, Hancong Wan, Qian Zhu, Yingchen Shen, Chong Chen, Li Su, Yufan Wang and Kun Liu
    Citation: Diabetology & Metabolic Syndrome 2025 17:106
    Content type: Research Published on:

  39. This study aimed to evaluate the associations between neutrophil percentage-to-albumin ratio (NPAR) and both all-cause and cardiovascular mortality in diabetic kidney disease (DKD) patients.

    Authors: Juntao Tan, Jinglong Du, Jiaxiu Liu, Wenlong Zhao and Yanbing Liu
    Citation: Diabetology & Metabolic Syndrome 2025 17:105
    Content type: Research Published on:

  40. Postherpetic neuralgia (PHN) and diabetes mellitus frequently coexist in clinical settings; however, the causal relationship between them remains unclear. Moreover, the potential mediating role of amino acids ...

    Authors: Haoning Lan, Zhangran Ai, Songchao Xu, Huili Li, Zhong Feng, Ruijuan Guo and Yun Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:104
    Content type: Research Published on:

  41. Type 2 diabetes mellitus (T2DM) is increasingly affecting people aged 15–34, posing a serious public health challenge due to its faster progression and higher complication risks. This study examines the global...

    Authors: Yang Zhou, Yupeng Chen, Yiting Tang, Shan Zhang, Zifan Zhuang and Qing Ni
    Citation: Diabetology & Metabolic Syndrome 2025 17:103
    Content type: Research Published on:

  42. Patients with diabetic nephropathy (DN) often present with lipid profile abnormalities. While associations between these parameters and DN have been suggested, confounding factors obscure causal relationships....

    Authors: Pengfei Xie, Weinan Xie, Zhaobo Wang, Ziwei Guo, Rumeng Tang, Haoyu Yang, Yu Wei, Ling Zhou, Yishan Huang, Linhua Zhao and Lili Zhang
    Citation: Diabetology & Metabolic Syndrome 2025 17:102
    Content type: Research Published on:

  43. we aimed to evaluate the association of interleukin-1β (IL-1β) gene single nucleotide polymorphisms (SNPs) and its interaction with smoking status on diabetic nephropathy (DN) risk in a Chinese Han population.

    Authors: Tianyue Xie and Zhuqi Tang
    Citation: Diabetology & Metabolic Syndrome 2025 17:101
    Content type: Research Published on:

  44. Glycemic variability (GV) is a key determinant of outcomes in critically ill patients, yet its impact on cerebral infarction patients in intensive care units (ICUs) remains underexplored. This study evaluates ...

    Authors: Hui Yang, Hongcai Wang and Yan Jiang
    Citation: Diabetology & Metabolic Syndrome 2025 17:100
    Content type: Research Published on:

  45. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a novel lipid indicator used for assessing the risk of cardiovascular diseases. This study was performed to ...

    Authors: Sikun Zhang and Zhaowei Zhu
    Citation: Diabetology & Metabolic Syndrome 2025 17:99
    Content type: Research Published on:

  47. Although studies had shown that Insulin resistance (IR) was correlated with the occurrence of sarcopenia, there were still many controversial conclusions. Therefore, we conducted a more comprehensive study on ...

    Authors: Zikai Jin, Liming Zheng, Chuanrui Sun, Bo Xu, Xiangyun Guo, Yili Zhang, Linghui Li and Xu Wei
    Citation: Diabetology & Metabolic Syndrome 2025 17:97
    Content type: Research Published on:

  48. The triglyceride-glucose (TyG) index, a recognized marker for insulin resistance, holds potential implications for skeletal health. However, its relationship with fragility fractures remains uncertain. We aime...

    Authors: Yuan Lou, Huan Chen, Fuli Man, Lina Zhang and Qi Pan
    Citation: Diabetology & Metabolic Syndrome 2025 17:96
    Content type: Research Published on:

  49. Diabetes retinopathy (DR) is a prevalent microvascular complication of type 2 diabetes mellitus (T2DM). This study investigated the correlation between renal function and DR, as well as the potential mediating...

    Authors: Youran Cai, Wanlu Qiu, Xiao Ma, Yuanting Yang, Ting Tang, Yuying Dong, Jian Chen and Qing Zhou
    Citation: Diabetology & Metabolic Syndrome 2025 17:95
    Content type: Research Published on:

  50. Few studies have evaluated changes in leukocyte telomere length (LTL) over a short time period (e.g. 1 week). LTL shortening is accelerated by exposure to inflammation and reactive oxygen species (ROS) damage.

    Authors: Janet M. Wojcicki, Elissa Epel, Jue Lin, Viva Tai, Jean-Marc Schwarz, Susan M. Noworolski, Ayca Erkin-Cakmak, Kathleen Mulligan, Alejandro Gugliucci and Rob H. Lustig
    Citation: Diabetology & Metabolic Syndrome 2025 17:94
    Content type: Brief Report Published on:

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Diabetology & Metabolic Syndrome

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