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  1. The significant burden of cardiovascular diseases underscores the necessity for identifying novel predictive markers that can forecast both cardiovascular diseases and mortality. In recent years, TyG-obesity-r...

    Authors: Mehrdad Rabiee Rad, Ghazal Ghasempour Dabaghi, Hossein Sadri, Bahar Darouei, Reza Amani-Beni and Sadegh Mazaheri-Tehrani
    Citation: Diabetology & Metabolic Syndrome 2025 17:59
  2. Insulin resistance is a crucial factor in the development of cardiovascular diseases (CVD), yet the relationship between the estimated glucose disposal rate (eGDR), an index reflecting insulin resistance, and ...

    Authors: Jing Tian, Hu Chen, Yan Luo, Zhen Zhang, Shiqiang Xiong and Hanxiong Liu
    Citation: Diabetology & Metabolic Syndrome 2025 17:58
  3. The aim of this study was to deeply explore the pathogenesis of obesity type 2 diabetes mellitus (O-T2DM) and search for potential biomarkers through high-throughput RNA sequencing technology. The study includ...

    Authors: Xian-Jie Zhen, Ren-tong Hu, Nan-Nan Liu, Jin-Fang Dou, Tao Wu, Yue-Lin Zhang, Chu-Yue Zhang, Li Ma and Guang-Jian Jiang
    Citation: Diabetology & Metabolic Syndrome 2025 17:57
  4. Drug management of type 2 diabetes (T2D) should comply with established guidelines. Still, little is known about how drug management of T2D in Switzerland has evolved over time. We aimed at assessing 15-year t...

    Authors: Ariane Pauli, Abdullah Alkandari and Pedro Marques-Vidal
    Citation: Diabetology & Metabolic Syndrome 2025 17:56
  5. Although many previous trials have formalized the blood glucose-lowering effect of the DASH diet, relevant reports in China remain limited. This study aimed to explore the anti-hyperglycaemic effect of the Chi...

    Authors: Jiaxian An, Guowei Liu, Wenjun Luo, Xiaomeng Zhou, Ying Mei, Ziyan Zhang, Li Zhao, Yao Huang and Lihong Mu
    Citation: Diabetology & Metabolic Syndrome 2025 17:55
  6. Hospital Hyperglycemia (HH) is linked to poorer outcomes, including higher mortality rates, increased ICU admissions, and extended hospital stays, and occurs in both people living with diabetes or not. The pre...

    Authors: Emerson Cestari Marino, Denise Momesso, Marcos Tadashi Kakitani Toyoshima, Maria Fernanda Ozorio de Almeida, Beatriz D. Schaan, Leandra Anália Freitas Negretto, Augusto Cezar Santomauro Junior, Priscilla Cukier, Paulo Roberto Rizzo Genestreti, Alina Coutinho Rodrigues Feitosa, Jorge Eduardo da Silva Soares Pinto, Rogerio Silicani Ribeiro, Rodrigo Nunes Lamounier, Ruy Lyra and Marcello Casaccia Bertoluci
    Citation: Diabetology & Metabolic Syndrome 2025 17:54
  7. Coronary Artery Calcification (CAC) is a major risk factor for various cardiovascular diseases. Low-Density Lipoprotein Cholesterol (LDL-C) is a significant factor in atherosclerotic cardiovascular diseases an...

    Authors: Zhi Zou, Yongbing Sun, Lijun Zou, Yang Zhou, Xinbei Lin, Jing Zhou, Zhonglin Li, Xiaoling Wu, Ling Wang, Xiaodong Li, Yong Wang, Yangxi Hu, Fengli Li, Jiancheng Zhang and Yongli Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:53
  8. Type 2 diabetes (T2DM) is known to have detrimental effects on renal health. Our study aimed to investigate the relationship between remnant cholesterol (remnant-C) and adverse renal outcomes in patients with ...

    Authors: Pan Yu, Qiongjing Yuan, Ling Huang, Lijian Tao, Zhangzhe Peng and Jiaxi Pu
    Citation: Diabetology & Metabolic Syndrome 2025 17:52
  9. Stroke is a leading cause of mortality and disability worldwide. Metabolic Score for Visceral Fat (METS-VF), a metric of visceral obesity, has emerged as a novel predictor of metabolic diseases. However, its a...

    Authors: Yue Cao, Weixing Wen, Hao Zhang, Weiwen Li, Guolin Huang and Yuli Huang
    Citation: Diabetology & Metabolic Syndrome 2025 17:50
  10. To investigate the glucose profile of Chinese individuals with type 1 diabetes (T1D) who also have metabolic syndrome.

    Authors: Yayu Fang, Wei Liu, Xiaoling Cai, Yu Zhu, Mingxia Zhang, Siqian Gong, Xiangqing Wang, Chu Lin, Rui Zhang, Sai Yin, Juan Li, Yongran Huo, Xiaodan Hu, Xiaoqi Xie and Linong Ji
    Citation: Diabetology & Metabolic Syndrome 2025 17:49
  11. Previous studies have emphasized the independent effects of anthropometric indices—including body mass index (BMI), A Body Shape Index (ABSI), waist-to-height ratio (WHtR), body roundness index (BRI), and Coni...

    Authors: Shuwu Wei, Weimin Jiang, Huijuan Zheng, Jiale Zhang, Jie Yang, Yaoxian Wang, Yang Liu, Liqiao Sun, Xinrong Li, Junping Wei and Weiwei Sun
    Citation: Diabetology & Metabolic Syndrome 2025 17:48
  12. Research indicates that there may be an association between plasma lipidome levels and the incidence of diabetic retinopathy (DR) in patients. However, the potential causality of this relationship is yet to be...

    Authors: Kai Yin, Lu Ding, Xueyan Li, Yuqi Zhang, Siyu Song, Liyuan Cao, Ruixue Deng, Min Li, Zirui Li, Qinjing Xia, Daqing Zhao, Xiangyan Li and Zeyu Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:47
  13. Tuberculosis (TB) and diabetes mellitus (DM) are global health challenges, each imposing significant morbidity and mortality. Observational studies suggest an increased TB risk in individuals with DM, yet caus...

    Authors: Ivaan Pitua, Raafidha Raizudheen, Mark Muyanja, Joseph Nyero and Morrish Okello Obol
    Citation: Diabetology & Metabolic Syndrome 2025 17:46
  14. Probiotics serve as promising candidates in type 2 diabetes mellitus (T2DM) therapy. Not only they presumably reduce the T2DM prevalence, but also keep down its complications. In the present study, we explored...

    Authors: Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed and Hebatalla Said Ali
    Citation: Diabetology & Metabolic Syndrome 2025 17:45
  15. To date, there is a lack of information on the use of flash glucose monitoring system (fCGM) in low-middle income countries, such as Brazil, as well as on digital health platforms most used to calculate the bo...

    Authors: Karla Santo, Josué Nieri, Karine Risério and Karla F. S. Melo
    Citation: Diabetology & Metabolic Syndrome 2025 17:44
  16. The relationship between body mass index (BMI) and sepsis prognosis remains highly controversial and uncertain. This study investigated the association between BMI and prognosis in patients with sepsis.

    Authors: Kunping Cui, Xiangnan Teng, Wei liu, Xiaoxiao Zhao, Shanling Xu and Lang Bai
    Citation: Diabetology & Metabolic Syndrome 2025 17:43
  17. To evaluate whether postoperative blood glucose increase (BGI) can serve as a predictive indicator for all-cause mortality within 3 months in patients with acute cerebral infarction with large vessel occlusion.

    Authors: Wensheng Zhang, Yajie Liu, Hongxing Zhou, Jie Li, Weifang Xing, Kaifeng Li, Yudi Li, Xiongjun He, Li Ling and Jinzhao He
    Citation: Diabetology & Metabolic Syndrome 2025 17:42
  18. Proprotein convertase subtilisin/kexin type 9 inhibitors effectively reduce LDL cholesterol and adverse cardiovascular events with a safety profile comparable to a placebo. Limited real-world data exists on th...

    Authors: Sultan Ibrahim Alraddadi, Hind Almodaimegh, Abdullah Kharbosh, Hadeel Alharbi, Ahmed Ibrahim Fathelrahman, Mona Yaser Alsheikh and Lama Alfehaid
    Citation: Diabetology & Metabolic Syndrome 2025 17:41
  19. Metabolic syndrome (MetS) is a global public health problem that significantly impacts human health and quality of life. The relationship between MetS and the C-reactive protein–albumin–lymphocyte (CALLY) inde...

    Authors: Lanlan Wu, Dunzheng Han, Yuting Xue, Shangfei He, Zhuang Ma, Shuwen Su, Peixin Li, Shenrong Liu and Haobin Zhou
    Citation: Diabetology & Metabolic Syndrome 2025 17:39
  20. The kidney reabsorption is essential for maintaining magnesium homeostasis. This study aims to explore the relationship between kidney reabsorption-related magnesium depletion score (MDS) and the occurrence of...

    Authors: Zhengxi Zhou and Xiaotian Yao
    Citation: Diabetology & Metabolic Syndrome 2025 17:38
  21. For patients considering bariatric surgery, it is essential to have clear answers to common questions to ensure the success of the procedure. Patients should understand that surgery is not a quick fix but a to...

    Authors: Amin Roshdy Soliman, Hesham Magd eldin Saleem, Amr Abel Hady El Meligi, Mervat Naguib, Rasha Sobh Mohamed, Ghada Rabie Abdelaziz, Maha Rakha, Shereen Abdelghaffar, Abd ElKhalek Hamed, Hany Abd El Rahman saeed Hammad, Eman O Mahmoud and Inass Shaltout
    Citation: Diabetology & Metabolic Syndrome 2025 17:37
  22. Adipose tissue plays a critical role in the development of metabolically unhealthy obesity (MUO), with distinct adipose depots demonstrating functional differences. This study aimed to investigate the unique c...

    Authors: Haoyue Guo, Zhiyi Zhang, Juntao Yang, Jiangfeng Liu, Hongwei Lin and Ningbei Yin
    Citation: Diabetology & Metabolic Syndrome 2025 17:36
  23. Increased glucagon levels are now recognized as a pathophysiological adaptation to counteract overnutrition in type 2 diabetes (T2D). This study aimed to elucidate the role of glucagon in peripheral nerve func...

    Authors: Hao Hua, Rui Wang, Yu-xian Xu, Feng Xu, Chun-hua Wang, Li-hua Zhao, Li-hua Wang, Cheng-wei Duan and Jian-bin Su
    Citation: Diabetology & Metabolic Syndrome 2025 17:35
  24. Of the numerous complications encountered by people with diabetes (PWD), the effect on mental health is concerning. Within mental health, diabetes distress (DD) occurs when a patient has unfavourable emotional...

    Authors: Madhur Verma, Shivani Sidana, Prakash Kumar, Omna Singh, Vandana Esht, Karthick Balasubramanian, Nitin Kapoor, Rakesh Kakkar and Sanjay Kalra
    Citation: Diabetology & Metabolic Syndrome 2025 17:34
  25. Altered tyrosine kinase signaling is associated with a variety of diseases. Tyrosine kinases can be classified into two groups: receptor type and nonreceptor type. Nonreceptor-type tyrosine kinases are subdivi...

    Authors: Mengjun Zhou, Qi Shen and Bo Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:33
  26. Disorders of insulin metabolism are strongly associated with a variety of psychological problems. The aim of this study was to investigate the differences in mindfulness levels among type 2 diabetes mellitus (...

    Authors: Xue Zhang, Rui Huang, Jiaxin Li, Mingyue Yang, Daowen Zhang, Cancan Liu and Kuanlu Fan
    Citation: Diabetology & Metabolic Syndrome 2025 17:32
  27. Growth differentiation factor 15 (GDF15) is significantly correlated with glycolipid metabolic disorders. Increased GDF15 levels are associated with obesity, insulin resistance, and diabetes as well as a poore...

    Authors: Wan-Chi Chuang, Chih-Hsun Chu, Cai-Sin Yao, Mei-Chih Wei, I-Lun Hsieh and Chia-Mei Liao
    Citation: Diabetology & Metabolic Syndrome 2025 17:31
  28. The present study comparatively evaluated glucose variability (GV) parameters derived from both continuous glucose monitoring (CGM) performed under standard conditions for a 24-h period and under usual everyda...

    Authors: R. Dimova, N. Chakarova and T. Tankova
    Citation: Diabetology & Metabolic Syndrome 2025 17:29
  29. Visceral fat (VF) was proved to be a more precise predictor of atherosclerotic cardiovascular disease (ASCVD) risk in individuals with type 2 diabetes mellitus (T2DM) than body mass index (BMI) itself. Even wh...

    Authors: Ming Jiao, Jiaoli Chen, Xiaoling Wang, Wenyu Tao, Yunhua Feng, Huijun Yang, Haiying Yang, Shanshan Zhao, Ying Yang and Yiping Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:28
  30. Stress hyperglycemia ratio is a novel indicator of acute coronary synthesis (ACS), which is closely related to the severity and complications of ACS and other cardiovascular diseases. However, its relationship...

    Authors: Shiqi Liu, Ziyang Wu, Gaoliang Yan, Yong Qiao, Yuhan Qin, Dong Wang and Chengchun Tang
    Citation: Diabetology & Metabolic Syndrome 2025 17:27
  31. In this study, we assessed whether the ratio of glucose management index (GMI) to glycated albumin (GA) was linked to microvascular complications in patients with type 2 diabetes mellitus (T2DM) who also posse...

    Authors: Yunqi Wu, Binshan Zhang, Xin Ma, Pei Yu, Saijun Zhou and Xinli Wang
    Citation: Diabetology & Metabolic Syndrome 2025 17:26
  32. Underserved and underrepresented populations often lack access to affordable, quality healthcare, educational resources, and nutritious foods, all of which contribute to increased risk of Type 2 Diabetes and g...

    Authors: Jessica Smith, Abey Martin, Jane Mundadan, Michael Roberts, Youssef Roman, Arturo Bravo-Nuevo and Farzaneh Daghigh
    Citation: Diabetology & Metabolic Syndrome 2025 17:25
  33. Prior studies on the link between socioeconomic status (SES) and diabetic microvascular complications have been inconclusive. This study aimed to explore whether SES is associated with the risk of diabetic ret...

    Authors: Yikeng Huang, Zhi Zheng, Haibing Chen and Chufeng Gu
    Citation: Diabetology & Metabolic Syndrome 2025 17:24
  34. The aim of our study was to assess the impact of high body mass index (BMI) on type 2 diabetes mellitus (T2DM) in different Socio-Demographic Development Index (SDI) regions using data from the Global Burden o...

    Authors: Yun-fa Ding, An-xia Deng, Teng-fei Qi, Hao Yu, Liang-ping Wu and Hong-bing Zhang
    Citation: Diabetology & Metabolic Syndrome 2025 17:23
  35. Various blood glucose (BG) variability-related indexes have been widely used to assess glycemic control and predict glycemic risks, but the association between BG variations and prognosis in non-diabetic patie...

    Authors: Jingyan Zhou, Zhiheng Chen, Hao-Neng Huang, Chun-Quan Ou and Xin Li
    Citation: Diabetology & Metabolic Syndrome 2025 17:22
  36. Previous studies have shown that weight change has a reverse J-shape association with all-cause mortality. However, its association with suicide mortality remains undetermined. In this study, we investigated t...

    Authors: Kyuho Kim, Jin-Hyung Jung, Yoo Hyun Um, Yu-Bae Ahn, Seung-Hyun Ko, Kyungdo Han and Jae-Seung Yun
    Citation: Diabetology & Metabolic Syndrome 2025 17:20
  37. As cardiovascular disease (CVD) morbidity and mortality increase yearly, this study aimed to explore the potential of the weight-adjusted-waist index (WWI) and its relation to long-term mortality in patients w...

    Authors: Hanbin Li, Wen Zhong, Hongxin Cheng, Shiqi Wang, Ran Li, Lu Wang, Chengqi He and Quan Wei
    Citation: Diabetology & Metabolic Syndrome 2025 17:19
  38. The relationship between the gut microbiome and metabolic dysfunction-associated fatty liver disease (MAFLD) has garnered increasing attention. However, the association between the dietary index for gut microb...

    Authors: Yangyang Zheng, Jinhui Hou, Shiqi Guo and Jinghai Song
    Citation: Diabetology & Metabolic Syndrome 2025 17:17
  39. Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by the presence of at least one cardiovascular disease (CVD) risk factor, underscoring its potential to elevate CVD risk in aff...

    Authors: Guanghui Ma, Guohou Xu and Haixia Huang
    Citation: Diabetology & Metabolic Syndrome 2025 17:16
  40. The triglyceride glucose-body mass index (TyG-BMI) is considered to be a reliable surrogate marker of insulin resistance (IR). However, limited evidence exists regarding its association with the severity of co...

    Authors: Lian Wang, Zijin Li, Rui Qiu, Li Luo and Xisheng Yan
    Citation: Diabetology & Metabolic Syndrome 2025 17:15
  41. Type 2 diabetes mellitus (T2D) is a global health concern with a rising prevalence, particularly in Brazil. Insulin therapy plays a crucial role in managing T2D, helping to maintain glucose and energy homeosta...

    Authors: André Gustavo Daher Vianna, Daniely Freitas Alves, Taís Silveira Assmann and Rosângela Roginski Réa
    Citation: Diabetology & Metabolic Syndrome 2025 17:14
  42. Type 2 diabetes mellitus (T2DM) is usually complicated by cardiovascular diseases, hyperglycemia, and obesity, which worsen the outcome for the patient. Since recent evidence underlines the epigenetic role of ...

    Authors: Xiaolei Miao, Maryam Davoudi, Zahra Alitotonchi, Ensieh Sadat Ahmadi, Fatemeh Amraee, Ashraf Alemi and Reza Afrisham
    Citation: Diabetology & Metabolic Syndrome 2025 17:13
  43. Epidemiological research on the association between heavy metals and congestive heart failure (CHF) in individuals with abnormal glucose metabolism is scarce. The study addresses this research gap by examining...

    Authors: Renyue Ji, Haisheng Wu, Hongli Lin, Yang Li and Yumeng Shi
    Citation: Diabetology & Metabolic Syndrome 2025 17:12
  44. Estimated glucose disposal rate (eGDR), is an index of insulin resistance. It is intimately correlated with inflammation and endothelial dysfunction, both of which are contributory factors in the pathogenesis ...

    Authors: Dawei Xing, Jing Xu, Xiaochun Weng and Xiaolu Weng
    Citation: Diabetology & Metabolic Syndrome 2025 17:11
  45. Formerly known as non-alcoholic fatty liver disease (NAFLD), metabolic dysfunction-associated steatotic liver disease (MASLD) has now become the most widespread chronic liver disease worldwide. The primary goa...

    Authors: Mengmeng Hu, Jingyu Yang, Beibei Gao, Zhoulu Wu, Ying Wu, Dandan Hu, Qiong Shen and Lei Chen
    Citation: Diabetology & Metabolic Syndrome 2025 17:10

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