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Prevalence and profile of diabetes kidney disease according to different diagnostic criteria in type 2 diabetes mellitus patients
Diabetology & Metabolic Syndrome volume 7, Article number: A28 (2015)
Background
Diabetes kidney disease (DKD) is the worldwide leading cause of end-stage renal disease. Diagnostic criteria have been recently revised.
Objective
The aim of this study was to evaluate the prevalence and clinical profile of type 2 DM patients according to the employed definition of DKD: previous diagnostic criteria as compared to the present one.
Materials and methods
566 type 2 DM outpatients from the Endocrine Unit ambulatory were included. DKD was defined by the presence of elevated urinary albumin excretion alone (UAE; >14 mg/l) -previous definition- or by the presence of elevated UAE and/or reduced (<60 ml/min/1.73 m2) glomerular filtration rate (GFR) -present definition.
Results
Mean age was 63±11 yrs., 37% men, 86% white, 10% smokers, DM duration 16 yrs. When evaluated by elevated UAE only, 50% of the patients presented DKD. Table 1 shows the profile of these patients (Fig 1). When defined by both UAE and GFR, 57% presented DKD, and Table 2 shows the profile of these patients (Fig 2).
Clinical and laboratory characteristics of DKD patients according to the presence of elevated UAE only.
Clinical and laboratory characteristics of DKD patients according to the presence of elevated UAE and/or reduced GFR.
Conclusion
DKD cases would be missed if only UAE is taken into account.
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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Coelli, S., Soares, A.A., Duarte, C.K. et al. Prevalence and profile of diabetes kidney disease according to different diagnostic criteria in type 2 diabetes mellitus patients. Diabetol Metab Syndr 7 (Suppl 1), A28 (2015). https://doi.org/10.1186/1758-5996-7-S1-A28
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DOI: https://doi.org/10.1186/1758-5996-7-S1-A28