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Table 3 The association between AIP index and the risk of CVD among participants with MASLD

From: Association between atherogenic index of plasma and all-cause mortality and cardiovascular disease among individuals with non-alcoholic fatty liver disease or metabolic dysfunction-associated steatotic liver disease

CVD

OR (95% CI)

Model 1

Model 2

Model 3

AIP index (continuous)

1.81 (1.33, 2.46)

1.94 (1.40, 2.70)

1.70 (1.17, 2.45)

 

P < 0.001

P < 0.001

P = 0.005

AIP index (quartiles)

   

Q1 (≤ 0.31)

Reference

Reference

Reference

Q2 (0.31–0.52)

1.45 (1.06, 1.99)

1.23 (0.90, 1.69)

1.16 (0.81, 1.65)

 

P = 0.0208

P = 0.189

P = 0.418

Q3 (0.52–0.74)

1.72 (1.26, 2.34)

1.65 (1.21, 2.23)

1.56 (1.11, 2.19)

 

P < 0.001

P = 0.001

P = 0.011

Q4 (≥ 0.74)

1.91 (1.41, 2.59)

2.05 (1.51, 2.79)

1.75 (1.24, 2.47)

 

P < 0.001

P < 0.001

P = 0.001

P for trend

P < 0.001

P < 0.001

P < 0.001

  1. Model 1: no covariates were adjusted
  2. Model 2: adjusted for age, gender and race/ethnicity
  3. Model 3: adjusted for age, gender, race/ethnicity, income, education, marital status, sedentary lifestyle, smokers, diabetes, hypertension and NFS
  4. *ORs were derived from univariate and multivariate logistic regression
  5. CVD: Cardiovascular disease; OR: Odds ratios; CI: Confidence intervals; AIP: Atherogenic Index of Plasma; Q1–Q4: Quartile 1-Quartile 4; NFS: Non-alcoholic fatty liver disease fibrosis score