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Table 2 The association between AIP index and the risk of CVD among participants with NAFLD

From: Association between atherogenic index of plasma and all-cause mortality and cardiovascular disease among individuals with non-alcoholic fatty liver disease or metabolic dysfunction-associated steatotic liver disease

CVD

OR (95% CI)

Model 1

Model 2

Model 3

AIP index (continuous)

2.03 (1.53, 2.70)

2.01 (1.49, 2.73)

1.72 (1.22, 2.43)

 

P < 0.001

P < 0.001

P = 0.002

AIP index (quartiles)

   

Q1 (≤ 0.25)

Reference

Reference

Reference

Q2 (0.25–0.48)

1.38 (1.01, 1.87)

1.33 (0.97, 1.84)

1.33 (0.93, 1.90)

 

P = 0.041

P = 0.079

P = 0.122

Q3 (0.48–0.71)

1.86 (1.39, 2.49)

1.68 (1.22, 2.31)

1.66 (1.17, 2.35)

 

P < 0.001

P = 0.001

P = 0.005

Q4 (≥ 0.71)

2.16 (1.62, 2.88)

1.97 (1.43, 2.70)

1.77 (1.24, 2.52)

 

P < 0.001

P < 0.001

P = 0.002

P for trend

P < 0.001

P < 0.001

P = 0.001

  1. Model 1: no covariates were adjusted
  2. Model 2: adjusted for age, gender and race/ethnicity
  3. Model 3: adjusted for age, gender, race/ethnicity, income, education, marital status, sedentary lifestyle, smokers, diabetes, hypertension and NFS
  4. *ORs were derived from univariate and multivariate logistic regression
  5. CVD: Cardiovascular disease; OR: Odds ratios; CI: Confidence intervals; AIP: Atherogenic Index of Plasma; Q1–Q4: Quartile 1-Quartile 4; NFS: Non-alcoholic fatty liver disease fibrosis score