Association between serum α-klotho levels and the incidence of diabetic kidney disease and mortality in type 2 diabetes: evidence from a Chinese cohort and the NHANES database

Kang, Yi; Jin, Qian; Zhou, Mengqi; Zheng, Huijuan; Li, Danwen; Zhou, Jingwei; Lv, Jie; Wang, Yaoxian

doi:10.1186/s13098-025-01711-x

Fig. 6

From: Association between serum α-klotho levels and the incidence of diabetic kidney disease and mortality in type 2 diabetes: evidence from a Chinese cohort and the NHANES database

The nonlinear relationship between α-klotho and all-cause as well as cardiovascular mortality. (A-C) Nonlinear relationship analysis of α-klotho with all-cause mortality. (A)overall population; (B) females (C) males. (D-F) Nonlinear relationship analysis of α-klotho with cardiovascular mortality. (D)overall population; (E) females; (F) males. The red line represents the hazard ratio (HR) of α-klotho levels, the blue dashed line indicates the α-klotho values at different thresholds, and the shaded area represents the 95% confidence interval

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Fig. 6

Diabetology & Metabolic Syndrome

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