Table 5 Top 10 consistently differentially methylated CpG sites across public and validation datasets
CpG site | Gene symbol | Public Δβ | Validation Δβ | Methylation | Consistency |
|---|---|---|---|---|---|
cg11924024 | PPARG | 0.15 | 0.13 | ↑ | ✓ |
cg18492887 | INS | −0.22 | −0.18 | ↓ | ✓ |
cg27610561 | GLUT4 | 0.18 | 0.16 | ↑ | ✓ |
cg05554724 | TNF | 0.13 | 0.11 | ↑ | ✓ |
cg26385555 | KCNQ1 | −0.17 | −0.15 | ↓ | ✓ |
cg11024682 | ADIPOQ | 0.20 | 0.17 | ↑ | ✓ |
cg19693031 | TXNIP | 0.16 | 0.14 | ↑ | ✓ |
cg25268100 | MTNR1B | −0.14 | −0.12 | ↓ | ✓ |
cg06500161 | ABCG1 | 0.19 | 0.16 | ↑ | ✓ |
cg19693031 | LEP | 0.16 | 0.13 | ↑ | ✓ |