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Table 3 Threshold effect analysis of eGDR on CVD risk stratified by glucose metabolism status

From: Association between estimated glucose disposal rate and future cardiovascular disease risk across glucose metabolism status: a prospective cohort study

Model

Normoglycemia

HR (95% CI) P value

Prediabetes

HR (95% CI) P value

Diabetes

HR (95% CI) P value

One-line linear regression

   

 One-line effect

0.87 (0.84, 0.90) < 0.0001

0.92 (0.89, 0.95) < 0.0001

0.88 (0.83, 0.92) < 0.0001

Two-piecewise regression

   

 Infection points of eGDR (mg/kg/min)

11.77

11.15

11.56

 < Infection points

0.86 (0.83, 0.89) < 0.0001

0.90 (0.86, 0.93) < 0.0001

0.86 (0.81, 0.91) < 0.0001

 ≥ Infection points

1.13 (0.92, 1.37) 0.2409

1.10 (0.97, 1.26) 0.1423

1.29 (0.99, 1.69) 0.0564

P for log-likelihood ratio test

0.025

0.010

0.015

  1. Models were adjusted for gender, age, living place, education level, marital status, drinking status, smoking status, CRP, WBC, platelets, FPG, BUN, Scr, UA, TG, HDL-c, LDL-c, BMI
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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