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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Human umbilical cord mesenchymal stem cell-derived exosomal miR-455-3p targets CAMK2N1 to improve trophoblast cell injury in gestational diabetes mellitus

Fig. 3

miR-455-3p derived from hucMSCs-Exos improves trophoblast cell injury in GDM. A qRT-PCR for miR-455-3p expression level in hucMSCs-Exos; B RT-qPCR for miR-455-3p expression level in hucMSCs transfected with miR-455-3p mimic; C qRT-PCR for miR-455-3p expression level in Exos isolated from miR-455-3p mimic-transfected hucMSCs; D RT-qPCR for miR-455-3p expression level in HRT-8/SVneo cells co-cultured with Exos-miR-455-3p mimic; E CCK-8 assay for cell proliferation; F Transwell assay for cell migration; G Flow cytometry for cell apoptosis. The t-test was used for comparisons between two groups, and ANOVA was used for comparisons among multiple groups, with Tukey’s test as the post hoc test. * indicates P < 0.05. All experiments were repeated more than three times

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