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Table 2 Multivariate Cox analysis of endpoint events in patients with diabetic kidney disease

From: Association between magnesium depletion score and all-cause and cause-specific mortality in patients with diabetic kidney disease

 

Events/Total

Model 1

Model 2

Model 3

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

All-cause mortality

2052/3179

      

 MDS = 0

35/89

Reference

0.003

Reference

0.002

Reference

0.004

 MDS = 1

116/212

1.581(1.083,2.307)

0.018

1.531(1.049,2.235)

0.027

1.724(1.178,2.523)

0.005

 MDS = 2

1675/2509

1.809(1.294,2.529)

< 0.001

1.825(1.305,2.551)

< 0.001

1.864(1.321,2.631)

< 0.001

 MDS ≥ 3

226/369

1.730(1.212,2.407)

0.003

1.767(1.237,2.523)

0.002

1.932(1.339,2.787)

< 0.001

Cardiovascular mortality

690/3179

      

 MDS = 0

6/89

Reference

0.008

Reference

0.006

Reference

0.015

 MDS = 1

37/212

2.908(1.227,6.892)

0.015

2.798(1.180,6.631)

0.019

3.391(1.428,8.054)

0.006

 MDS = 2

575/2509

3.613(1.616,8.078)

0.002

3.648(1.631,8.156)

0.002

3.839(1.700,8.672)

0.002

 MDS ≥ 3

72/369

3.191(1.387,7.341)

0.006

3.669(1.421,7.521)

0.005

3.688(1.586,8.577)

< 0.001

  1. Note: HR, hazard ratio; CI, confidence interval;
  2. Model 1: unadjusted model
  3. Model 2: adjusted for age and sex
  4. Model 3: adjusted for age, sex, race, Blood glucose control, BMI, Magnesium intake, Heavy drinking, HbA1c, TC, TG, HDL-C, FBG, Serum phosphorus, Statins use, Insulin use, Metformin use, Diuretic use, PPI use, eGFR, Hypertension and CVD