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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Electroacupuncture modulates the gut-brain axis via the PI3K/Akt pathway to improve feeding behavior, body weight, glucolipid metabolism, and reduce insulin resistance in T2DM rats

Fig. 3

Expression of ZO-1, Occludin and Claudin-1 in colon tissues of rats (\(\bar{x} \pm \mathrm{SE}\), n = 6). A: Protein expression of ZO-1, Occludin, Claudin-1 in colon, (1)ZO-1, (2)Occludin, (3)Claudin-1, (4)a diagram depicting protein expression bands. B: The mRNA expression of ZO-1, Occludin, Claudin-1in colon, (1)ZO-1, (2)Occludin, (3)Claudin-1. C: Immunohistochemical staining of colon tissue of rats, (1)-(3)Quantitative analyses of ZO-1, Occludin and Claudin-1 based on immunohistochemical images according to groups; (4)Representative images of immunohistochemical staining of ZO-1, Occludin, Claudin-1 in colon, scale = 20 Î¼m. Con is the control group, T2DM is the model group, EA is the intervention group, and EA + LY294002 is the intervention + PI3K inhibitor group. Compared to the Con group, **P<0.01, *P<0.05; compared to the T2DM group,##P<0.01, #P<0.05; compared to the EA group, △△P<0.01, â–³P<0.05

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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