Fig. 1

Body weight, food intake, FBG, blood lipids, and IR in rats (\(\bar x \pm \mathrm{SE}\), n = 6). A: Weekly body weight for each group, in grams (g), with w1-4 representing modeling period and w5-9 intervention period; B: Weekly average food intake for each group, in grams (g), with w1-4 representing modeling period and w5-9 intervention period. C: FBG levels before modeling, after modeling and after intervention; D: Blood lipids, (1)TG, (2)TC, (3)LDL, (4)HDL. E: IR, (1)INS, (2)HOMA-IR, (3)HOMA-ISI. Con is the control group, T2DM is the model group, EA is the intervetion group, and EA + LY294002 is the intervention + PI3K inhibitor group. Compared to the Con group, **P<0.01, *P<0.05; compared to the T2DM group,##P<0.01, #P<0.05; compared to the EA group, △△P<0.01, △P<0.05