Table 1 Baseline characteristics of participants categorized by SHR
Variables | Overall n = 3703 | T1 (≤ 0.95) n = 1236 | T2 (0.95–1.25) n = 1233 | T3 (> 1.25) n = 1234 | P-value |
|---|---|---|---|---|---|
Age (years) | 68.4 (56.8, 79.1) | 69.6 (57.9, 79.9) | 68.9 (56.8, 79.8) | 67.1 (56.0, 77.5) | 0.003 |
Male, n (%) | 2163 (58.4) | 715 (57.9) | 733 (59.5) | 715 (57.9) | 0.664 |
BMI (kg/m2) | 28.6 (24.5, 33.8) | 28.7 (24.3, 33.5) | 28.2 (24.5, 33.5) | 29.1 (24.7, 34.3) | 0.025 |
SOFA | 4.0 (2.0, 6.0) | 3.0 (1.0, 5.0) | 3.0 (2.0, 5.0) | 5.0 (2.0, 8.0) | <0.001 |
SAPS II | 33.0 (26.0, 42.0) | 32.0 (25.0, 40.0) | 33.0 (26.0, 40.0) | 36.0 (28.0, 45.0) | <0.001 |
Comorbidities, n (%) | Â | Â | Â | Â | Â |
 CKD | 756 (20.4) | 255 (20.6) | 211 (17.1) | 290 (23.5) | <0.001 |
 HF | 1179 (31.8) | 365 (29.5) | 364 (29.5) | 450 (36.5) | <0.001 |
 RF | 1075 (29.0) | 269 (21.8) | 322 (26.1) | 484 (39.2) | <0.001 |
 Hypertension | 1833 (49.5) | 618 (50.0) | 643 (52.2) | 572 (46.4) | 0.014 |
 Diabetes | 898 (24.3) | 298 (24.1) | 247 (20.0) | 353 (28.6) | <0.001 |
 COPD | 238 (6.4) | 73 (5.9) | 74 (6.0) | 91 (7.4) | 0.250 |
 Malignancy | 562 (15.2) | 174 (14.1) | 216 (17.5) | 172 (13.9) | 0.019 |
 ACS | 405 (10.9) | 97 (7.9) | 127 (10.3) | 181 (14.7) | <0.001 |
Interventions, n (%) | Â | Â | Â | Â | Â |
 RRT | 258 (7.0) | 63 (5.1) | 70 (5.7) | 125 (7.0) | <0.001 |
 Diuretics | 1195 (32.3) | 371 (30.0) | 364 (29.5) | 460 (37.3) | <0.001 |
 Vasoactive drugs | 738 (19.9) | 180 (14.6) | 192 (15.6) | 366 (29.7) | <0.001 |
Laboratory tests | Â | Â | Â | Â | Â |
 WBC (K/uL) | 10.7 (8.0, 14.3) | 9.2 (7.1, 11.9) | 10.8 (9.2, 13.7) | 12.6 (9.2, 16.8) | <0.001 |
 Hemoglobin (g/dL) | 11.9 (10.2, 13.4) | 11.8 (10.3, 13.4) | 12.1 (10.5, 13.5) | 11.6 (9.9, 13.4) | <0.001 |
 RDW (%) | 14.0 (13.2, 15.1) | 14.0 (13.2, 15.1) | 13.8 (13.1, 14.9) | 14.1 (13.2, 15.3) | <0.001 |
 Platelet (K/uL) | 204.0 (159.0, 259.0) | 208.0 (162.0, 259.0) | 206.0 (163.0, 256.0) | 200.5 (152.0, 262.0) | 0.124 |
 Creatinine (mg/dL) | 1.0 (0.8, 1.4) | 1.0 (0.7, 1.4) | 1.0 (0.8, 1.3) | 1.1 (0.8, 1.6) | <0.001 |
 Albumin (g/dL) | 3.3 (2.9, 3.7) | 3.4 (2.9, 3.8) | 3.4 (2.9, 3.8) | 3.3 (2.8, 3.7) | <0.001 |
 BUN (mg/dL) | 19.0 (14.0, 29.0) | 18.0 (13.0, 28.0) | 18.0 (13.0, 26.0) | 21.0 (15.0, 34.0) | <0.001 |
 TC (mg/dL) | 156.0 (124.1, 193.0) | 155.0 (125.0, 191.0) | 158.0 (125.0, 195.0) | 156.0 (121.6, 192.2) | 0.118 |
 TG (mg/dL) | 119.0 (87.0, 202.6) | 119.0 (87.0, 191.6) | 119.0 (85.0, 197.0) | 127.0 (91.3, 219.5) | 0.014 |
 ALT (U/L) | 25.0 (17.0, 38.0) | 25.0 (16.0, 31.0) | 25.0 (18.0, 36.0) | 25.0 (20.0, 53.0) | <0.001 |
 AST (U/L) | 33.0 (23.0, 53.0) | 33.0 (21.0, 42.0) | 33.0 (24.0, 47.0) | 33.0 (27.0, 80.0) | <0.001 |
 Sodium (mmol/L) | 138.0 (137.0, 140.0) | 138.0 (138.0, 141.0) | 138.0 (137.0, 140.0) | 138.0 (136.0, 140.0) | <0.001 |
 Potassium (mmol/L) | 4.1 (3.7, 4.5) | 4.0 (3.7, 4.4) | 4.0 (3.7, 4.4) | 4.2 (3.7, 4.6) | <0.001 |
 Chlorine (mmol/L) | 103.0 (100.0, 107.0) | 104.0 (101.0, 107.0) | 103.0 (100.0, 106.0) | 102.0 (98.0, 106.0) | <0.001 |
 Glucose (mg/dL) | 137.0 (109.0, 191.0) | 104.0 (92.0, 126.0) | 131.0 (116.0, 153.0) | 204.0 (164.0, 277.0) | <0.001 |
 HbA1c (%) | 5.9 (5.5, 6.8) | 6.0 (5.6, 7.2) | 5.8 (5.4, 6.4) | 6.0 (5.4, 6.9) | <0.001 |