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Table 2 IPTW-weighted logistic regression analysis on the association between the TyG index and fragility fractures

From: Association between the Triglyceride-glucose index and fragility fractures among US adults: insights from NHANES

 

Model 1

Model 2

Model 3

OR (95% CI)

P value

OR (95% CI)

Pvalue

OR (95% CI)

P value

TyG

1.83 (1.34, 2.49)

 < 0.001

1.79 (1.26, 2.55)

0.001

1.94 (1.31, 2.88)

 < 0.001

Q1[3.62,4.45]

Reference

–

Reference

–

Reference

–

Q2(4.45,4.67]

1.16 (0.80, 1.70)

0.435

0.86 (0.58, 1.27)

0.451

0.87 (0.59, 1.29)

0.488

Q3(4.67.4.91]

1.41 (0.98, 2.03)

0.067

0.99 (0.68, 1.44)

0.963

1.03 (0.70, 1.50)

0.887

Q4(4.91,7.09]

1.75 (1.23, 2.48)

0.002

1.39 (0.97, 1.99)

0.074

1.47 (1.00, 2.15)

0.048

  1. Model 1: unadjusted
  2. Model 2: adjusted for age, sex, and educational level
  3. Model 3: further adjusted for BMI, alcohol consumption, SBP, DBP, HbA1c, albumin, alkaline phosphatase, 25(OH)D, diabetes, hypertension, hyperlipidemia, coronary artery disease, chronic kidney disease, and medication treatments, including insulin drugs, oral hypoglycemic agents, antihypertensive drugs, and lipid-lowering drugs
  4. Abbreviations: IPTW, inverse probability of treatment weighting; TyG, triglyceride-glucose; OR, odds ratio; CI, confidence interval; Q, quartile; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, glycated hemoglobin; 25(OH)D, 25-hydroxyvitamin D