Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content

Table 2 NT-proBNP-Associated MACCEs according to BMI threshold

From: Body mass index modifies the major adverse cardiovascular and cerebral events risk of NT-proBNP in patients with acute coronary syndrome

 

Events/Total

HR (95% CI) *

P value

Whole cohort

   

 Ln NT-proBNP, per 1-SD

1996/11,757

1.49 (1.39‒1.60)

< 0.001

 Quintiles of

 NT-proBNP

Quintile 1

164/2354

1.00 (reference)

NA

Quintile 2

254/2349

1.28 (1.05‒1.56)

0.015

Quintile 3

331/2352

1.41 (1.16‒1.71)

0.001

Quintile 4

467/2351

1.74 (1.43‒2.12)

< 0.001

Quintile 5

780/2351

2.43 (1.95‒3.02)

< 0.001

Normoweight (BMI 18.5–23.9 kg/m2)

  

 Ln NT-proBNP, per 1-SD

661/3477

1.42 (1.26‒1.61)

< 0.001

 Quintiles of

 NT-proBNP

Quintile 1

38/576

1.00 (reference)

NA

Quintile 2

74/654

1.38 (0.93‒2.05)

0.110

Quintile 3

92/648

1.42 (0.96‒2.10)

0.079

Quintile 4

131/710

1.30 (0.87‒1.94)

0.194

Quintile 5

326/889

1.91 (1.25‒2.91)

0.003

Overweight (BMI 24.0–27.9 kg/m2)

  

 Ln NT-proBNP, per 1-SD

890/5386

1.51 (1.36‒1.67)

< 0.001

 Quintiles of

 NT-proBNP

Quintile 1

79/1103

1.00 (reference)

NA

Quintile 2

110/1084

1.22 (0.91‒1.64)

0.186

Quintile 3

158/1102

1.49 (1.12‒1.98)

0.006

Quintile 4

228/1082

2.08 (1.56‒2.77)

< 0.001

Quintile 5

315/1015

2.70 (1.96‒3.73)

< 0.001

Obese (BMI ≥ 28.0 kg/m2)

   

 Ln NT-proBNP, per 1-SD

445/2894

1.51 (1.29‒1.75)

< 0.001

 Quintiles of

 NT-proBNP

Quintile 1

47/675

1.00 (reference)

NA

Quintile 2

70/611

1.33 (0.91‒1.94)

0.139

Quintile 3

81/602

1.37 (0.94‒2.01)

0.103

Quintile 4

108/559

1.84 (1.25‒2.73)

0.002

Quintile 5

139/447

2.72 (1.74‒4.25)

< 0.001

  1. *Multivariable Cox proportional hazards regression model was adjusted for age (continuous), sex, diagnosis of AMI, history of dyslipidemia, history of myocardial infarction, history of arrhythmia, SBP (quartiles), LVEF (quartiles), eGFR (quartiles), hs-CRP (quartiles), LDL-C (quartiles), smoking status, PCI, and in-hospital medication (antiplatelet therapy, β-blocker, ACEI or ARB, and statins). P value for interaction: Ln NT-proBNP×BMI (continuous) = 0.013
Back to article page

Diabetology & Metabolic Syndrome

ISSN: 1758-5996

Contact us