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Table 6 Haplotype analysis on association between IL-1β gene and DN risk

From: Association of the interaction between interleukin-1β gene polymorphism and smoking status with the diabetic nephropathy risk in a Chinese Han population

Haplotypes (rs1143634 and rs3917356)

Frequencies

OR (95%CI)

P-values*

T2DM patients with DN

(N = 412)

T2DM patients without DN

(N = 416)

C

C

0.4811

0.5689

1.00

-

T

C

0.2312

0.2168

1.24 (0.68–1.85)

0.763

C

T

0.1964

0.1719

1.38 (0.74–2.08)

0.526

T

T

0.0913

0.0424

1.64 (1.17–2.16)

0.001

  1. *Adjusted for gender, age, TC, LDL-C, SBP, DBP, BMI and smoking