Table 1 Description and primer sequences used for genotyping for 4 SNPs of IL-1β gene

rs1143634

+ 3954 C > T

2:112832813 (GRCh38)

2:113590390 (GRCh37)

Coding sequence variant, synonymous variant

C > T

F: 5′- -CTCAGGTGTCCTCGAAGAAATCAAA-3′

R: 5′- GCTTTTTTGCTGTGAGTCCCG-3′

rs16944

-511 (A > G)

2:112837290 (GRCh38)

2:113594867 (GRCh37)

Upstream transcript variant, 2KB upstream variant

A > G

F: 5′- TGGCATTGATCTGGTTCATC-3′

R: 5′- GTTTAGGAATCTTCCCACTT-3′

rs3917356

C > T

2:112834786 (GRCh38)

2:113592363 (GRCh37)

Intron variant

C > T

F:5′- CTAGCTAGGTCAGTTGTGCAGGTTCG-3′

R: 5′- AGCTGCAGCCAACAAGTTATGC-3′

rs1143627

G > A

2:112836810 (GRCh38)

2:113594387 (GRCh37)

Upstream transcript variant, 2KB upstream variant

G > A

F: 5′- TCGAAGAGGTTTGGTATCTGCC − 3′

R: 5′- GCTTCCACCAATACTCTTTTCCC − 3′