Fatty pancreas disease in newly diagnosed type 2 diabetes patients: a case–control study on relationships with glycemic control and exocrine function

Table 3 Comparison of demographic, clinical, laboratory parameters and ultrasound findings in T2DM and control groups

Variable	T2DM (n = 63)	Control (n = 63)	p-value
Age, years	51.6 ± 10,7	51.5 ± 8.0	0.948
Gender (male), n (%)	32 (50.8)	32 (50.8)	1.0
BMI (kg/m²)	32.4 ± 6.6	31.4 ± 4.5	0.324
Waist-to-hip ratio	0.97 ± 0.07	0.97 ± 0.07	0.633
Body fat percentage (%)	32.6 ± 9.3	32.1 ± 7.8	0.743
Trunk fat percentage (%)	30.7 ± 7,6	30.9 ± 6.6	0.872
Trunk fat weight, kg	14.5 ± 5.0	14.3 ± 4.4	0.841
Hypertension, n (%)	26 (41.3)	7 (11.1)	< 0.001
CVD, n (%)	10 (15.9)	1 (1.6)	0.005
Fasting Glucose (mg/dl)	138 (108–220)	92 (86–97)	< 0.001
Fasting Insulin (µIU/mL)	17.2 ± 9,1	11.3 ± 5.2	< 0.001
HbA1c (%)	7.5 (6.8–10.5)	5.5 (5.3–5.6)	< 0.001
C-Peptide (ng/mL)	3.3 (2.4–4.5)	2.9 (2.3–3.1)	0.006
HOMA-IR	5.7 (3.7–9.1)	2.5 (1.6–2.9)	< 0.001
Fatty Pancreas Disease Grade	1 (0–3)	1 (0–2)	0.123
Hepatic Steatosis Grade	2 (0–3)	1 (0–3)	0.018
Fecal Elastase Level (µg/g)	158.5 ± 90.9	290.4 ± 67.8	< 0.001
Exocrine Pancreatic Insufficiency, n (%)
No insufficiency	18 (28.6)	58 (92.1)	< 0.001
Mild-to-moderate insufficiency	24 (38.1)	5 (7.9)
Severe insufficiency	21 (33.3)	0 (0.0)

Independent samples t-test was used for variables expressed as mean ± standard deviation, Mann–Whitney U tests were used for variables expressed as medians (interquartile ranges), and chi-square tests were used for categorical variables expressed as numbers (%). T2DM type 2 diabetes mellitus, BMI body mass index, CVD cardiovascular disease, HOMA-IR homeostasis model assessment for insulin resistance

ISSN: 1758-5996