Table 10 Regression results from three MR methods for UACR
From: Association of diabetic nephropathy with lipid metabolism: a Mendelian randomization study
Outcome | Exposure | Method | β | SE | OR(95%CI) | P |
|---|---|---|---|---|---|---|
TC | UACR | MR-Egger | 0.2228 | 0.1778 | 1.2496 (0.8819~1.7706) | 0.2655 |
WME | -0.0623 | 0.0590 | 0.9396 (0.8369~1.0548) | 0.2910 | ||
IVW | -0.0584 | 0.0445 | 0.9433 (0.8644~1.0293) | 0.1898 | ||
TG | MR-Egger | -0.0667 | 0.1693 | 0.9354 (0.6713~1.3035) | 0.7097 | |
WME | -0.0172 | 0.0343 | 0.9829 (0.9190~1.0513) | 0.6155 | ||
IVW | -0.0327 | 0.0389 | 0.9678 (0.8968~1.0445) | 0.4003 | ||
LDL-C | MR-Egger | -0.0859 | 0.2287 | 0.9177 (0.5862~1.4366) | 0.7226 | |
WME | -0.0543 | 0.0505 | 0.9471 (0.8579~1.0456) | 0.2819 | ||
IVW | -0.0139 | 0.0529 | 0.9862 (0.8890~1.0939) | 0.7923 | ||
HDL-C | MR-Egger | -0.0631 | 0.2386 | 0.9389 (0.5881~1.4987) | 0.8045 | |
WME | -0.0013 | 0.0752 | 0.9987 (0.8617~1.1574) | 0.9859 | ||
IVW | 0.0059 | 0.0573 | 1.0059 (0.8990~1.1255) | 0.9186 | ||
ApoA1 | MR-Egger | 0.1963 | 0.1515 | 1.2168 (0.9042~1.6376) | 0.2518 | |
WME | 0.0352 | 0.0341 | 1.0358 (0.9689~1.1074) | 0.3019 | ||
IVW | 0.0072 | 0.0400 | 1.0072 (0.9313~1.0893) | 0.8579 | ||
ApoB | MR-Egger | -0.0258 | 0.2104 | 0.9745 (0.6452~1.4719) | 0.9072 | |
WME | -0.0128 | 0.0308 | 0.9872 (0.9294~1.0487) | 0.6772 | ||
IVW | -0.0124 | 0.0481 | 0.9876 (0.8988~1.0852) | 0.7959 |