Table 3 Threshold effect analysis of MLR and other inflammatory biomarkers on CVD using a two-piecewise linear regression model in model 3

CVD

Fitting by standard linear model

3.78 (1.83, 7.82) 0.0003

1.14 (1.05, 1.25) 0.0034

1.01 (0.99, 1.02) 0.1718

1.37 (0.99, 1.87) 0.0520

Fitting by two-piecewise linear model

 Breakpoint (K)

0.16

1.53

111.3

0.01

 OR1 (< K )

0.01 (0.01, 20.90) 0.5257

1.33 (0.99, 1.78) 0.0567

1.00 (0.99, 1.01) 0.4126

0.75 (0.01, 1.27) 0.2308

 OR2 (> K )

4.02 (1.91, 8.43) 0.0002

1.10 (0.98, 1.23) 0.1007

1.00 (0.99, 1.01) 0.1283

1.34 (0.98, 1.85) 0.0674

 OR2 / OR1

0.67 (0.09, 1.42) 0.4174

0.83 (0.58, 1.17) 0.2881

1.00 (0.99, 1.01) 0.3838

0.02 (0.01, 1.55) 0.2341

Logarithmic likelihood ratio test P-value

0.032

0.288

0.390

0.222