Skip to main content

Table 2 Association between MLR and other inflammatory biomarkers with CVD

From: Association between monocyte-to-lymphocyte ratio and cardiovascular diseases: insights from NHANES data

Index

Continuous or categories

Model 13

Model 24

Model 35

OR1 (95%CI2)

P- value

OR (95%CI)

P- value

OR (95%CI)

P- value

MLR

MLR as continuous variable

25.49 (20.67, 31.44)

< 0.0001

3.74 (2.96, 4.73)

< 0.0001

3.78 (1.83, 7.82)

0.0003

 

Tertile 1

Reference

 

Reference

 

Reference

 
 

Tertile 2

1.23 (1.13, 1.34)

< 0.0001

1.00 (0.91, 1.10)

0.9947

1.15 (0.87, 1.53)

0.3330

 

Tertile 3

2.59 (2.40, 2.80)

< 0.0001

1.40 (1.28, 1.52)

< 0.0001

1.39 (1.05, 1.83)

0.0194

 

P for trend

< 0.0001

 

< 0.0001

 

0.0143

 

SIRI

SIRI as continuous variable

1.42 (1.38, 1.46)

< 0.0001

1.24 (1.20, 1.28)

< 0.0001

1.14 (1.05, 1.25)

0.0034

 

Tertile 1

Reference

 

Reference

 

Reference

 
 

Tertile 2

1.34 (1.23, 1.45)

< 0.0001

1.22 (1.11, 1.33)

< 0.0001

1.04 (0.78, 1.37)

0.8086

 

Tertile 3

2.47 (2.29, 2.67)

< 0.0001

1.78 (1.63, 1.94)

< 0.0001

1.34 (1.03, 1.75)

0.0322

 

P for trend

< 0.0001

 

< 0.0001

 

0.0119

 

AISI

AISI as continuous variable

1.01 (1.00, 1.01)

< 0.0001

1.01 (1.01, 1.02)

< 0.0001

1.01 (0.99, 1.02)

0.1718

 

Tertile 1

Reference

 

Reference

 

Reference

 
 

Tertile 2

1.18 (1.09, 1.28)

< 0.0001

1.15 (1.05, 1.25)

0.0017

1.10 (0.85, 1.42)

0.4599

 

Tertile 3

1.69 (1.57, 1.82)

< 0.0001

1.49 (1.38, 1.62)

< 0.0001

1.08 (0.84, 1.39)

0.5309

 

P for trend

< 0.0001

 

< 0.0001

 

0.6177

 

CAR

CAR as continuous variable

1.87 (1.64, 2.13)

< 0.0001

1.63 (1.41, 1.89)

< 0.0001

1.37 (0.99, 1.87)

0.0520

 

Tertile 1

Reference

 

Reference

 

Reference

 
 

Tertile 2

1.58 (1.41, 1.76)

< 0.0001

1.22 (1.08, 1.37)

0.0017

1.06 (0.86, 1.31)

0.5774

 

Tertile 3

2.13 (1.92, 2.37)

< 0.0001

1.49 (1.38, 1.62)

< 0.0001

1.16 (0.94, 1.44)

0.1615

 

P for trend

< 0.0001

 

< 0.0001

 

0.1527

 
  1. In sensitivity analysis, MLR, SIRI, AISI, and CAR were converted from continuous variables to categorical variables (tertiles)
  2. 1OR: Odd ratio
  3. 295% CI: 95% confidence interval
  4. 3Model 1: No covariates were adjusted
  5. 4Model 2: Adjusted for age, sex, and race
  6. 5Model 3: Adjusted for sex, age, race, marital status, education level, BMI, smoking status, alcohol consumption, TC, HDL-C, AST, ALT, PIR, total bilirubin, serum total calcium, RA, DKD, asthma, close relative had heart attack, COPD, hypertension and diabetes
Back to article page

Diabetology & Metabolic Syndrome

ISSN: 1758-5996

Contact us