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Table 1 Baseline characteristics according to MLR tertiles

From: Association between monocyte-to-lymphocyte ratio and cardiovascular diseases: insights from NHANES data

MLR

Overall

Tertile 1

Tertile 2

Tertile 3

P-value

(0.03–0.22)

(0.22–0.30)

(0.30–2.50)

N

46,289

14,952

15,825

15,512

 

MLR

0.28 ± 0.12

0.17 ± 0.03

0.25 ± 0.02

0.40 ± 0.12

< 0.001

SIRI

1.21 ± 0.88

0.68 ± 0.31

1.06 ± 0.44

1.88 ± 1.12

< 0.001

AISI

311.93 ± 285.45

181.44 ± 110.29

275.74 ± 231.79

474.55 ± 363.83

< 0.001

CAR

0.11 ± 0.23

0.10 ± 0.17

0.09 ± 0.16

0.13 ± 0.33

< 0.001

Age, years

    

< 0.001

 20–40

17,058 (36.81%)

6349 (42.42%)

6180 (39.03%)

4529 (29.15%)

 

 41–60

15,952 (34.43%)

5572 (37.23%)

5556 (35.09%)

4824 (31.05%)

 

 > 60

13,327 (28.76%)

3046 (20.35%)

4099 (25.89%)

6182 (39.79%)

 

Sex, n (%)

    

< 0.001

 Male

22,995 (49.63%)

5609 (37.48%)

7888 (49.81%)

9498 (61.14%)

 

 Female

23,342 (50.37%)

58 (62.52%)

7947 (50.19%)

6037 (38.86%)

 

Race, n (%)

    

< 0.001

 Mexican American

8328 (17.97%)

3008 (20.10%)

3031 (19.14%)

2289 (14.73%)

 

 Other Hispanic

4116 (8.88%)

1428 (9.54%)

1445 (9.13%)

1243 (8.00%)

 

 Non-Hispanic White

19,173 (41.38%)

4486 (29.97%)

6603 (41.70%)

8084 (52.04%)

 

 Non-Hispanic Black

10,128 (21.86%)

4224 (28.22%)

3160 (19.96%)

2744 (17.66%)

 

 Other Races

4592 (9.91%)

1821 (12.17%)

1596 (10.08%)

1175 (7.56%)

 

Education level, n (%)

    

< 0.001

 Less than high school

12,441 (26.85%)

4185 (27.96%)

4207 (26.57%)

4049 (26.06%)

 

 High school or GED

10,776 (23.26%)

3343 (22.34%)

3628 (22.91%)

3805 (24.49%)

 

 Above high school

23,061 (49.77%)

7427 (49.63%)

7983 (50.41%)

7651 (49.25%)

 

 Others

58 (0.13%)

11 (0.07%)

17 (0.11%)

30 (0.19%)

 

Marital status, n (%)

    

< 0.001

 Married

20,373 (52.54%)

6526 (51.74%)

7118 (53.70%)

6729 (52.13%)

 

 Never married

7147 (18.43%)

2398 (19.01%)

2461 (18.57%)

2288 (17.73%)

 

 Living with a partner

2908 (7.50%)

1091 (8.65%)

1000 (7.54%)

817 (6.33%)

 

 Others

8347 (21.53%)

2598 (20.60%)

2676 (20.19%)

3073 (23.81%)

 

BMI, n (%)

    

< 0.001

 Normal weight

13,481 (29.58%)

4206 (28.43%)

4573 (29.30%)

4702 (30.98%)

 

 Overweight

15,284 (33.53%)

4710 (31.84%)

5339 (34.21%)

5235 (34.49%)

 

 Obese

16,813 (36.89%)

5877 (39.73%)

5695 (36.49%)

5241 (34.53%)

 

Smoking status, n (%)

    

< 0.001

 ≥100 cigarettes lifetime

20,758 (44.84%)

6228 (41.63%)

6944 (43.87%)

7586 (48.91%)

 

 < 100 cigarettes lifetime

25,539 (55.16%)

8731 (58.37%)

8884 (56.13%)

7924 (51.09%)

 

PIR, n (%)

    

< 0.001

 Low income

12,984 (30.83%)

3975 (29.29%)

4559 (31.72%)

4450 (31.41%)

 

 Medium income

15,897 (37.75%)

5077 (37.41%)

5377 (37.42%)

5443 (38.42%)

 

 High income

13,229 (31.42%)

4521 (33.31%)

4435 (30.86%)

4273 (30.16%)

 

Alcohol consumption, n (%)

    

< 0.001

 yes

28,782 (78.40%)

9087 (79.02%)

9985 (79.61%)

9710 (76.64%)

 

 no

7928 (21.60%)

2412 (20.98%)

2557 (20.39%)

2959 (23.36%)

 

Hypertension, n (%)

24,394 (52.64%)

7257 (48.49%)

7977 (50.38%)

9160 (58.96%)

< 0.001

Diabetes, n (%)

7378 (15.92%)

2355 (15.73%)

2321 (14.66%)

2702 (17.39%)

< 0.001

RA

1032 (2.24%)

311 (2.08%)

300 (1.90%)

421 (2.73%)

< 0.001

DKD

2885 (6.26%)

752 (5.04%)

859 (5.45%)

1274 (8.28%)

< 0.001

Asthma

6101 (13.25%)

2021 (13.56%)

2032 (12.89%)

2048 (13.32%)

0.217

Close relative had heart attack

4157 (12.31%)

1378 (12.26%)

1357 (11.81%)

1422 (12.89%)

0.048

COPD

257 (2.74%)

51 (1.80%)

62 (1.93%)

144 (4.32%)

< 0.001

TC, mg/dL

194.36 ± 41.44

197.78 ± 42.36

195.15 ± 40.20

190.27 ± 41.44

< 0.001

ALT, U/L

25.40 ± 24.67

24.55 ± 16.97

25.56 ± 20.28

26.05 ± 33.40

< 0.001

AST, U/L

25.26 ± 19.07

24.35 ± 13.48

25.02 ± 15.33

26.38 ± 25.83

0.004

HDL-C, mg/dL

52.57 ± 15.86

52.33 ± 15.44

52.40 ± 15.77

52.99 ± 16.34

0.042

Total bilirubin, mg/dL

0.65 ± 0.32

0.62 ± 0.29

0.65 ± 0.31

0.68 ± 0.35

< 0.001

Serum total calcium, mg/dL

9.41 ± 0.38

9.41 ± 0.38

9.41 ± 0.37

9.40 ± 0.38

0.054

CHF, n (%)

1385 (2.99%)

247 (1.65%)

312 (1.97%)

826 (5.33%)

< 0.001

CHD, n (%)

1722 (3.72%)

288 (1.93%)

442 (2.79%)

992 (6.41%)

< 0.001

Angina pectoris, n (%)

1190 (2.57%)

252 (1.69%)

350 (2.21%)

588 (3.80%)

< 0.001

Heart attack, n (%)

1823 (3.94%)

342 (2.29%)

460 (2.91%)

1021 (6.58%)

< 0.001

Stroke, n (%)

1611 (3.48%)

411 (2.75%)

444 (2.81%)

756 (4.87%)

< 0.001

CVD, n (%)

3696 (7.98%)

998 (6.67%)

1279 (8.08%)

2425 (15.61%)

< 0.001

  1. MLR, monocyte-to-lymphocyte ratio; SIRI, systemic inflammation response index; AISI, aggregate index of systemic inflammation; CAR, C-reactive protein and albumin ratios; GED, general educational development; BMI, body mass index; PIR, family income to poverty ratio; RA, rheumatoid arthritis; DKD, diabetic kidney disease; COPD, chronic obstructive pulmonary disease; TC, total cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL-C, high-density lipoprotein-cholesterol; CHF, congestive heart failure; CHD, coronary heart disease; CVD, cardiovascular diseases