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Table 3 Conditional logistic regression for 201 cases and their 201 matched controls with normal levels of fasting plasma glucose (FPG) and 2-hour plasma glucose (2-hPG) and risk for incident type 2 diabetes mellitus

From: Elevated levels of PAI-1 precede the occurrence of type 2 diabetes mellitus

 

Crude

OR (95% CI)

 

Adjusted model†

OR (95% CI)

BMI

2.91 (1.63–5.21)

 

1.94 (0.94-4.00)

Family history of T2DM

3.60 (1.34–9.70)

 

6.44 (1.37–30.3)

Smoking

   
 

Never

1

  
 

Ever

1.71 (0.68–4.35)

  

Physical activity

   
 

Active

1

  
 

Inactive

0.79 (0.36–1.73)

  

Hypertension

4.00 (1.34–11.97)

 

1.81 (0.16–4.04)

Total cholesterol

0.92 (0.62–1.36)

  

PAI-1

2.61 (1.77–7.36)

 

2.68 (1.03–6.95)

FPG

0.84 (0.53–1.33)

  

2-hPG

2.46 (1.31–4.62)

 

2.30 (0.83–6.36)

  1. Odds ratio (OR) and 95% CI per 1 SD increment. Only varaibles with crude p < 0.2 were included in the adjusted model
  2. T2DM: type 2 diabetes mellitus
  3. PAI-1: plasminogen activator inhibitor-1
  4. FPG: fasting plasma glucose
  5. 2-hPG: 2-hour plasma glucose
  6. † Adjusted model: Adjusted for body mass index, family history of T2DM, hypertension, PAI-1 and 2hPG
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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