Fig. 2

Proteome analysis. (2 A) 159 downregulated and 122 upregulated proteins in VA compared to SA. Correlation analysis was shown in the heatmap dia gram. (2B) The top 5 upregulated (red) and downregulated (blue) proteins in VA compared to SA were shown in the volcano plot. (2 C) The top 10 upregulated (red) and downregulated (blue) proteins were shown in the radar plot, with the second ring showed the log2-transformed FC values, and the third ring represented the average quantification levels. (2D) GO enrichment for BP, CC, and MF categories, selecting the top 5 upregulated (red) and downregulated (blue) pathways in VA compared to SA for each category, longer bars indicated smaller p-values while larger points represented more genes. (2E) KEGG enrichment bubble chart (right) combined with a Sankey-bubble plot (left). The Sankey plot represented proteins included in each pathway, while the bubble plot displayed bubble size as the number of proteins in the pathways and bubble color as the p-value. The top 10 upregulated and downregulated pathways were selected for visualization