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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: CircRNA-mediated ceRNA regulatory networks: transcriptomic insights into obesity type 2 diabetes progression and treatment strategies

Fig. 2

Enrichment analysis results of gene modules. A KEGG pathways of the hub genes in the darkmagenta module are plotted according to the adjusted p-value (y-axis) and the non-statistical Z-score calculated by GoPlot (x-axis). The area of each circle represents the number of genes of that pathway. B KEGG pathways of the hub genes in the lightsteelblue1 module. C, D GSEA of oxidative phosphorylation (C) and apoptosis (D) pathways between control and O-T2DM groups. There is a scale panel below, with black vertical lines representing significant genes. The left side (red) represents genes that are upregulated in the O-T2DM group compared to the control group, while the right side (blue) represents genes that are downregulated

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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