Vascular volume changes in radiological patterns of usual interstitial pneumonia in patients with type 2 diabetes

Table 3 Factors associated with UIP patterns in T2DM patients – logistic regression analysis

	Univariate		Multivariate
	OR (95% CI)	P	OR (95% CI)	P
IPVV (mL)	0.99 (0.99–1.00)	0.008	0.98 (0.97–0.99)	< 0.001
Age (years)	1.10 (1.05–1.16)	< 0.001	1.12 (1.04–1.20)	0.002
Female (%)	0.98 (0.43–2.22)	0.959
Disease duration (months)	1.02 (0.96–1.07)	0.567
Smoking history (years)	2.68 (1.26–5.74)	0.011	7.44 (2.30–24.05)	< 0.001
BMI (kg/m^2)	1.04 (0.89–1.22)	0.650
FPG (mmol/L)	1.23 (1.02–1.48)	0.027	1.51 (1.11–2.05)	0.009
HbA1c (mmol/mol)	1.04 (1.01–1.07)	0.022	1.04 (0.99–1.09)	0.105
Baseline C-peptide levels (ng/mL)	2.70 (1.14–6.38)	0.024
Fasting insulin (uU/ml)	0.93 (0.83–1.04)	0.175
TG (mmol/L)	0.76 (0.45–1.28)	0.302
TC (mmol/L)	0.86 (0.60–1.25)	0.429
LDL-C (mmol/L)	0.87 (0.56–1.36)	0.545
HDL-C (mmol/L)	0.61 (0.15–2.45)	0.487
Hcy (umol/L)	1.21 (1.02–1.43)	0.027
SCr (umol/L)	1.00 (0.99–1.01)	0.523
SUA (umol/L)	1.00 (0.99–1.00)	0.201
SUA/SCr	0.760 (0.533–1.084)	0.130
Cys-C (mg/L)	6.67 (1.09–40.77)	0.04	3.79 (0.38–38.25)	0.259
LDH (U/L)	1.02 (1.00–1.03)	0.018	1.01 (1.00–1.03)	0.117
Use of insulin	0.82 (0.37–1.83)	0.625

IPVV intrapulmonary vascular volume, BMI body mass index, FPG fasting plasma glucose, 2hPG 2-h post-load plasma glucose, HbA1c glycated hemoglobin, TG triglycerides, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, Hcy homocysteine, SCr serum creatinine, SUA serum uric acid, SUA/SCr serum uric acid/serum creatinine ratios, Cys-C cystatin C, LDH, lactate dehydrogenase

ISSN: 1758-5996