Table 3 Univariate and multivariate analysis of risk factors for 28-day mortality in critically ill patients with CS

Age, years

1.00

0.98, 1.02

0.868

–

–

–

1.10

0.98, 1.01

0.4504

–

–

–

Sex

 Male

–

–

–

–

–

–

–

–

–

–

–

–

 Female

1.10

0.77, 1.57

0.612

–

–

–

1.92

0.73, 1.16

0.485

–

–

–

BMI

 Normal weight

–

–

–

–

–

–

–

–

–

–

–

–

 Underweight

1.59

0.89, 4.64

0.269

2.28

0.52, 1.61

0.408

2.55

1.12, 1.55

0.027

2.42

1.02, 1.57

0.039

 Overweight

0.67

0.92, 1.26

0.365

0.74

0.69, 1.22

0.068

1.04

0.92, 1.96

0.104

1.28

1.38, 1.99

0.221

 Obesity

0.98

0.78,1.05

0.221

0.92

0.99, 1.25

0.335

1.06

0.83, 1.53

0.062

1.15

1.86, 2.45

0.709

 Severe obesity

1.22

1.43, 2.07

0.525

1.14

0.68, 2.18

0.774

1.32

0.79, 2.08

0.531

1.46

0.88, 1.40

0.521

Comorbidities

 Hypertension

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

1.27

1.10, 2.14

0.018

1.45

1.21, 2.09

0.024

1.25

0.71, 1.43

0.072

–

–

–

 Diabetes

  No

–

–

–

–

–

–

–

–

–

–

  Yes

1.04

0.38, 1.20

0.046

1.02

0.78, 1.22

0.018

1.73

1.06, 1.12

0.011

1.12

0.92, 2.03

0.021

 AHF

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

1.10

0.69, 1.45

0.550

–

–

–

1.13

0.67, 1.22

0.231

–

–

–

 CKD

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

1.26

1.12, 1.88

0.042

1.04

0.81, 1.32

0.412

1.74

1.32, 2.24

0.004

1.22

0.82, 2.67

0.286

 ARF

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

1.68

1.03, 1.76

0.032

1.36

0.92, 2.10

0.028

1.02

1.21, 1.87

0.214

–

–

–

 Severity index

  Sofa score

1.13

1.08, 1.19

 < 0.001

1.55

0.78, 0.94

 < 0.001

1.12

1.22, 1.79

 < 0.001

1.92

0.83, 1.74

 < 0.001

  Sirs score

1.44

1.17, 1.77

 < 0.001

1.21

0.93, 1.58

0.152

1.35

1.09, 1.96

 < 0.001

1.56

0.79, 1.48

0.008

 Inflammation indicator

  CRP, mg/L

2.09

1.22, 1.72

0.107

–

–

–

1.21

0.92, 1.22

0.008

1.82

1.02, 1.63

0.212

  NLR

1.20

0.92, 1.98

0.002

1.32

1.20, 2.21

0.014

1.11

1.04, 1.59

0.047

1.59

1.21, 1.29

0.032

 Arterial blood gas

  PH

0.81

0.44, 9.88

0.92

–

–

–

0.75

0.55, 0.73

 < 0.001

4.62

1.05, 4.45

0.006

  PaCO₂, mmHg

1.01

0.99, 1.02

0.325

–

–

–

1.03

0.99, 1.31

0.541

–

–

–

  PaO₂, mmHg

0.90

1.19, 1.89

0.032

0.83

0.99, 1.20

0.028

0.69

1.53, 1.70

0.035

0.94

1.30, 1.69

0.040

  PaO₂/FiO₂

0.92

1.11, 1.56

0.006

0.96

1.00, 1.58

0.042

0.74

1.00, 1.04

0.032

0.89

1.20, 2.52

0.014

  Lactate, mmol/L

1.04

1.17, 1.13

 < 0.001

1.22

1.01, 1.44

0.021

2.02

1.06, 1.08

 < 0.001

1.27

1.09, 1.36

 < 0.001

Medicine use

 Eepinephrine use

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

1.11

0.74, 1.64

0.618

–

–

–

1.19

0.67, 1.40

0.023

1.82

1.02, 2.29

0.389

 Norepinephrine use

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

1.32

0.92, 1.89

0.170

–

–

–

2.13

1.10, 3.44

 < 0.001

1.27

1.29, 3.04

 < 0.001

 Furosemide use

  No

–

–

–

–

–

–

–

–

–

–

–

  Yes

0.41

1.07, 2.33

0.020

0.36

0.23, 0.59

 < 0.001

0.84

0.42, 0.96

 < 0.001

0.52

0.76, 1.69

 < 0.001