Association between sarcopenia and the foot-ankle function in type 2 diabetic foot ulcer

Table 5 Multivariate logistic regression analysis of factors influencing foot-ankle function in patients with DF

	B	SE	Wald	P	OR (95%CI)
foot-ankle function = 1	-5.086	2.828	3.233	0.072	0.006 (0.000, 1.580)
foot-ankle function = 2	-2.437	2.810	0.752	0.386	0.087 (0.000, 21.556)
foot-ankle function = 3	0.578	2.812	0.042	0.837	1.782 (0.007, 441.110)
Age	0.082	0.034	5.880	0.015^*	1.085 (1.016, 1.159)
Sex (versus female)	-0.799	0.459	3.035	0.081	0.450 (0.183, 1.105)
BMI (kg/m2)	-0.022	0.070	0.094	0.760	0.979 (0.853, 1.124)
Duration of DM (years)	-0.034	0.028	1.503	0.220	0.967 (0.916, 1.020
TcPO2	-0.077	0.025	9.683	0.002^*	0.926 (0.883, 0.972)
CRP	0.003	0.009	0.116	0.733	1.003 (0.986, 1.020)
Severity of Foot Ulcer = 1	-0.969	0.788	1.510	0.219	0.380 (0.081, 1.780)
Severity of Foot Ulcer = 2	-1.113	0.696	2.562	0.109	0.328 (0.084, 1.284)
Severity of Foot Ulcer = 3	reference
Sarcopenia Grading = 0	-2.884	1.342	4.591	0.032^*	0.056 (-5.592, -0.252)
Sarcopenia Grading = 1	-2.495	1.222	4.168	0.041^*	0.082 (-5.024, -0.161)
Sarcopenia Grading = 2	-2.393	1.182	4.098	0.043^*	0.091 (0.009, 0.927)
Sarcopenia Grading = 3	reference

B: Partial Regression Coefficient; SE: Standard Error; OR: Odds Ratio; 95% CI: 95% Confidence Interval; TcPO₂, transcutaneous oxygenpressure; CRP, C-reactive protein
We used ordinal logistic regression analysis, and adjusted for age, sex, BMI, duration of diabetes, TcPO2, CRP, severity of foot ulcer, and sarcopenia grading in the model. *P < 0.05 indicates statistical significance
The assignment of foot-ankle function is as follows: Excellent foot-ankle function group is assigned a value of 1, Good group is assigned a value of 2, Fair group is assigned a value of 3, and Poor foot-ankle function group is assigned a value of 4. The assessment of severity of foot ulcer is as follow: Mild degree of foot ulceration is assigned as value of 1, Moderate is assigned as value of 2, Severe is assigned as value of 3. Evaluation of sarcopenia severity is assigned as follows: No sarcopenia is assigned a value of 0, Reduced muscle mass is assigned a value of 1, Sarcopenia is assigned a value of 2, and Severe sarcopenia is assigned a value of 3

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