Association between sarcopenia and the foot-ankle function in type 2 diabetic foot ulcer

Table 3 Comparison of biochemical indicators between the Sarcopenia and non-sarcopenia groups in DF patients

	DF with sarcopenia (n = 44)	DF without sarcopenia (n = 64)	Wald χ²	P value
HbA1c (%)	8.6 (7.7, 10.95)	8.3 (7.3, 9.45)	1.379	0.240
FBG (mmol/L)	5.23 (7.45, 8.92)	6.87 (5.49, 9.13)	1.134	0.287
ALB (g/L)	37.57 (32.75, 40.25)	39.17 (36.02, 41.95)	0.748	0.387
ALT (U/L)	16.5 (10.33, 22.53)	16.05 (12, 20.63)	0.510	0.475
AST (U/L)	15 (12.9, 19.73)	15.2 (12.93, 18.45)	0.621	0.431
TG (mmol/L)	0.99 (0.73, 1.45)	1.09 (0.83, 1.52)	0.052	0.820
TC (mmol/L)	4.48 ± 1.19	4.74 ± 1.20	0.802	0.370
HDL-C (mmol/L)	1.13 (0.94, 1.25)	1.07 (0.90, 1.32)	1.764	0.184
LDL-C (mmol/L)	2.70 ± 1.06	2.99 ± 0.99	0.752	0.386
sCr (umol/L)	77.35 (56.75, 101.8)	64.6 (52.25, 87.73)	3.904	0.048^*
UA (umol/L)	324.05 ± 107.56	313.28 ± 79.40	0.483	0.487
UACR (mg/g)	243.26 (28.33, 1045.85)	45.69 (15.45, 236.71)	0.220	0.639
WBC (*10⁹/L)	9 (6.11, 11.73)	7.53 (6.29, 9.54)	0.204	0.652
CRP (mg/L)	20.21 (9.37, 53.46)	10.07 (1.94, 17.09)	1.452	0.228

The generalized linear models (GLM) was used to analyzed the relationship between DF with or without sarcopenia and the key parameters. Age, sex, BMI, duration of diabetes, and Wagner classification were adjusted. *P < 0.05 indicates statistical significance
DF, diabetic foot; HbA1c, Hemoglobin A1c; FBG, fasting blood glucose; ALB, Albumin; ALT, Alanine transaminase; AST, Aspartate transaminase; TG, triglyceride; TC, total cholesterol; LDL-C, low-density-lipoprotein cholesterol; HDL-C, high-density-lipoprotein cholesterol; sCr, serum creatine; UA, uric acid; UACR, Urinary albumin creatinine ratio; WBC, white blood cell; CRP, C-reactive protein

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