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Table 2 Patients’ demographic and clinical characteristics

From: Effects of glucagon-like peptide-1 receptor agonists on cardiovascular outcomes in high-risk type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials

First Author

Publication Year

Sample Data

T/I/C(n)

Age

(Mean ± SD)

Male (n, %)

T2DM

Duration (Years)

Cardiovascular

Death

I/C (n)

Primary Composite

Outcome

I/C (n)

Myocardial

Infarction

I/C (n)

Stroke

I/C (n)

All-Cause

Death

I/C (n)

HF

Hospitalization

I/C (n)

UA

Hospitalization

I/C (n)

Hernandez

2018

9,463/ 4,731/ 4,732

64.1 ± 8.7

3304, 70.0%

14.1

122/ 130

338/ 428

181/ 240

94/ 108

196/ 205

188/ 218

/

Gerstein

2019

9,901/ 4,949/ 4,952

66.2 ± 6.5

5312, 53.7%

10.6

317/ 346

594/ 663

223/ 231

158/ 205

536/ 592

213/ 226

88/ 77

Pfeffer

2015

6,068/ 3,034/ 3,034

60.1 ± 9.6

4207, 69.3%

9.3

158/ 156

399/ 406

261/ 270

60/ 67

223/ 211

127/ 122

10/ 11

Marso a

2016

9,340/ 4,668/ 4,672

64.3 ± 7.2

6003, 64.3%

12.9

219/ 278

608/ 694

292/ 339

173/ 199

381/ 447

218/ 248

122/ 124

Marso b

2016

3,297/ 1,648/ 1,649

64.7 ± 7.4

2002, 60.7%

14.2

44/ 46

108/ 146

47/ 64

27/ 44

62/ 60

59/ 54

22/ 27

Husain

2019

3,183/ 1,591/ 1,592

66.0 ± 7.0

2176, 68.4%

15.0

15/ 30

61/ 76

37/ 31

12/ 16

23/ 45

21/ 24

11/ 7

Holman

2017

14,752/ 7,356/ 7,396

62.0 ± 8.9

5603, 38.0%

12.0

340/ 383

839/ 905

483/ 493

187/ 218

507/ 548

219/ 231

602/ 570

Gerstein

2021

4,076/ 2,717/ 1,359

64.5 ± 8.2

2732, 67.0%

15.4

75/ 50

189/ 125

91/ 58

47/ 31

111/ 69

40/ 31

6/ 4

Perkovic

2024

3,533/ 1,767/ 1,766

66.6 ± 9.0

2464, 69.7%

15.0

123/ 169

/

52/ 64

63/ 51

227/ 279

133/ 175

/

  1. T, total sample size; I: intervention group; C: control group; T2DM, type 2 diabetes mellitus; HF: heart failure; UA: unstable angina; SD: standard deviation