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Table 1 Baseline characteristics of participants stratified by quartiles of estimated glucose disposal rate

From: Association of estimated glucose disposal rate with incident cardiovascular disease under different metabolic and circadian rhythm states: findings from a national population-based prospective cohort study

Characteristic

Overall

N = 6,507

Quartiles of eGDR

p-value

Q1

N = 1,627

Q2

N = 1,627

Q3

N = 1,629

Q4

N = 1,624

Gender, n (%)

     

0.015

 Female

3,564 (55)

935 (57)

875 (54)

907 (56)

847 (52)

 

 Male

2,943 (45)

692 (43)

752 (46)

722 (44)

777 (48)

 

Age,years

58.00 (52.00,64.00)

60.00 (54.00,66.00)

60.00 (54.00,66.00)

56.00 (49.00,62.00)

57.00 (50.00,63.00)

 < 0.001

Marital, n (%)

5,817 (89)

1,447 (89)

1,388 (85)

1,505 (92)

1,477 (91)

 < 0.001

Local, n (%)

     

 < 0.001

 City

2,229 (34)

678 (42)

516 (32)

553 (34)

482 (30)

 

 Rural

4,278 (66)

949 (58)

1,111 (68)

1,076 (66)

1,142 (70)

 

Education, n (%)

     

 < 0.001

 Elementary school and below

4,528 (70)

1,133 (70)

1,213 (75)

1,069 (66)

1,113 (69)

 

 Junior high school

1,314 (20)

320 (20)

288 (18)

382 (23)

324 (20)

 

 High school and above

665 (10)

174 (11)

126 (7.7)

178 (11)

187 (12)

 

Hypertension, n (%)

2,995 (46)

1,622 (100)

1,317 (81)

9 (0.6)

47 (2.9)

 < 0.001

Diabetes, n (%)

956 (15)

429 (26)

246 (15)

181 (11)

100 (6.2)

 < 0.001

Chronic kidney disease, n (%)

1,344 (21)

356 (22)

373 (23)

321 (20)

294 (18)

0.003

CES-D, scoring

7.00 (3.00, 12.00)

7.00 (3.00, 12.00)

7.00 (3.00, 13.00)

7.00 (3.00, 12.00)

8.00 (3.00, 12.00)

0.033

Sleep time, hours

6.00 (5.00, 8.00)

7.00 (5.00, 8.00)

6.00 (5.00, 8.00)

7.00 (5.00, 8.00)

6.75 (5.00, 8.00)

0.052

Drinking, n (%)

     

 < 0.001

 Never

3,984 (61)

1,004 (62)

973 (60)

1,020 (63)

987 (61)

 

 Former

512 (7.9)

170 (10)

140 (8.6)

94 (5.8)

108 (6.7)

 

 Current

2,011 (31)

453 (28)

514 (32)

515 (32)

529 (33)

 

Smoking, n (%)

     

 < 0.001

 Never

4,035 (62)

1,068 (66)

960 (59)

1,051 (65)

956 (59)

 

 Former

521 (8.0)

169 (10)

124 (7.6)

135 (8.3)

93 (5.7)

 

 Current

1,951 (30)

390 (24)

543 (33)

443 (27)

575 (35)

 

SBP, mmHg

125.00 (113.00, 140.00)

142.00 (132.00, 153.50)

137.00 (125.00, 149.50)

116.50 (109.00, 124.00)

113.50 (106.00, 121.75)

 < 0.001

DBP, mmHg

74.00 (66.50, 82.50)

83.00 (74.50, 90.00)

79.00 (72.00, 87.00)

70.00 (64.50, 76.00)

67.50 (62.00, 73.50)

 < 0.001

Waist,cm

84.50 (77.80, 92.00)

94.20 (90.00, 99.10)

81.50 (76.40, 87.00)

87.00 (84.00, 91.00)

75.20 (71.20, 78.35)

 < 0.001

BMI, kg/m2

23.22 (20.96, 25.88)

26.31 (24.31, 28.57)

22.28 (20.32, 24.66)

24.01 (22.43, 25.63)

20.70 (19.25, 22.17)

 < 0.001

BUN, mg/dL

15.07 (12.55, 18.15)

15.04 (12.72, 18.12)

15.27 (12.52, 18.35)

15.04 (12.44, 18.07)

14.99 (12.46, 17.95)

0.47

FBG, mg/dL

102.06 (94.50, 111.96)

106.74 (98.46, 120.24)

102.42 (95.22, 112.14)

101.52 (94.32, 109.98)

98.37 (91.80, 106.38)

 < 0.001

TC, mg/dL

191.37 (168.17, 216.11)

199.49 (175.90, 225.39)

190.98 (168.94, 214.56)

190.59 (168.17, 214.95)

184.41 (161.99, 208.18)

 < 0.001

TG, mg/dL

103.54 (74.34, 150.45)

130.98 (92.93, 191.16)

101.78 (74.34, 148.68)

103.54 (73.46, 144.26)

85.85 (63.72, 120.36)

 < 0.001

HDL, mg/dL

49.48 (40.98, 59.92)

44.85 (37.50, 53.35)

51.42 (41.75, 61.47)

49.10 (40.59, 58.76)

54.51 (45.23, 64.56)

 < 0.001

LDL, mg/dL

115.59 (94.72, 138.40)

121.78 (99.36, 145.36)

114.05 (93.17, 135.70)

117.14 (96.26, 138.79)

110.18 (91.24, 132.22)

 < 0.001

hs-CRP, mg/L

0.99 (0.53, 2.04)

1.46 (0.79, 2.84)

0.96 (0.51, 1.95)

0.92 (0.54, 1.78)

0.72 (0.42, 1.47)

 < 0.001

HbA1c, %

5.20 (4.90, 5.40)

5.30 (5.00, 5.70)

5.10 (4.80, 5.40)

5.20 (4.90, 5.40)

5.00 (4.80, 5.30)

 < 0.001

UA, mg/dL

4.25 (3.54, 5.08)

4.56 (3.78, 5.42)

4.28 (3.55, 5.09)

4.18 (3.53, 5.00)

4.02 (3.39, 4.78)

 < 0.001

eGDR

9.48 (7.08, 11.04)

6.29 (5.76, 6.71)

7.91 (7.49, 8.49)

10.47 (10.08, 10.77)

11.58 (11.30, 11.95)

 < 0.001

Elevated waist circumference, n (%)

3,809 (59)

1,601 (98)

764 (47)

1,304 (80)

140 (8.6)

 < 0.001

Elevated serum triglycerides, n (%)

1,637 (25)

654 (40)

400 (25)

363 (22)

220 (14)

 < 0.001

Reduced serum HDL-C, n (%)

2,508 (39)

877 (54)

577 (35)

655 (40)

399 (25)

 < 0.001

Elevated blood pressure, n (%)

3,342 (51)

1,624 (100)

1,367 (84)

183 (11)

168 (10)

 < 0.001

Elevated plasma glucose, n (%)

3,780 (58)

1,160 (71)

968 (59)

908 (56)

744 (46)

 < 0.001

Short sleep, n (%)

1,889 (29)

423 (26)

504 (31)

472 (29)

490 (30)

0.010

Depression, n (%)

2,390 (37)

567 (35)

628 (39)

574 (35)

621 (38)

0.044

Metabolic syndrome, n (%)

2,801 (43)

1,397 (86)

730 (45)

531 (33)

143 (8.8)

 < 0.001

Circadian syndrome, n (%)

2,384 (37)

1,154 (71)

628 (39)

476 (29)

126 (7.8)

 < 0.001

Heart Disease, n (%)

416 (6.4)

124 (7.6)

118 (7.3)

96 (5.9)

78 (4.8)

0.003

Stroke, n (%)

304 (4.7)

136 (8.4)

79 (4.9)

47 (2.9)

42 (2.6)

 < 0.001

Cardiovascular diseases, n (%)

679 (10)

244 (25)

182 (11)

135 (8)

118 (7)

 < 0.001

  1. BMI body mass index, BUN blood urea nitrogen, DBP diastolic blood pressure, DM diabetes mellitus, eGDR estimated glucose disposal rate, FBG fasting blood glucose, HbA1c glycosylated hemoglobin A1c, HDL high density lipoprotein, hsCRP high-sensitivity C-reactive protein, LDL low density lipoprotein, SBP systolic blood pressure, TC total cholesterol, TG triglycerides, UA uric acid, WC waist circumference