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Table 2 Weighted multivariate liner regression analysis of association between TyG and α-Klotho

From: The association between the triglyceride-glucose index and serum anti-aging protein α- Klotho: a population-based study

 

Model 1

Model 2

Model 3

Model 4

 

β(95%CI)P-Value

β(95%CI)P-Value

β(95%CI)P-Value

β(95%CI)P-Value

TYG

-16.59(-36.34, 3.16)

-12.72(-32.62, 7.19)

-10.63(-32.31,11.04)

-74.07(-100.29,-47.85)***

TYG (quartiles)

    

Q1

Reference

Reference

Reference

Reference

Q2

-15.70(-49.03,17.63)

-14.85(-48.22,18.52)

-16.85(-50.42,16.72)

-35.72(-68.97, -2.46) *

Q3

-40.58(-73.89,-7.28)*

-35.71(-69.14,-2.28)*

-35.31(-69.28,-1.35)*

-68.36(-103.52,-33.20)***

Q4

-45.59(-78.90,-12.29)**

-40.42(-73.94,-6.90)*

-38.74(-74.28,-3.20) *

-113.37(-153.24,-73.50)***

P for trend

0.003

0.010

0.021

< 0.001

  1. Model 1: no adjustment for any variables
  2. Model 2: adjusted for age, gender and ethnicity
  3. Model 3: adjusted for Model 2 plus BMI, marital status, PIR, education level, smoking status, hypertension, diabetes, stroke, congestive heart failure and coronary heart disease
  4. Model 4: adjusted for Model 3 plus uric acid, FG, HDL-C and GGT
  5. CI, confidence interval, * p < 0.05, ** p < 0.01, *** p < 0.001