Table 1 Weighted characteristics of the study population based on TyG quartiles
TyG Quartiles | |||||
|---|---|---|---|---|---|
Variables | Q1(n = 642) | Q2(n = 615) | Q3(n = 652) | Q4(n = 659) | P-Value |
Age (years) | 57.12 ± 10.81 | 56.23 ± 10.55 | 57.50 ± 9.95 | 57.56 ± 10.13 | < 0.001 |
Gender | < 0.001 | ||||
Male | 45.6 | 50.8 | 58.5 | 59.0 | |
Female | 54.4 | 49.2 | 41.5 | 41.0 | |
Ethnicity | < 0.001 | ||||
Mexican American | 3.2 | 4.7 | 5.0 | 6.4 | |
Non-Hispanic White | 74.4 | 77.7 | 78.5 | 78.9 | |
Non-Hispanic Black | 14.5 | 9.5 | 7.2 | 4.6 | |
Other Hispanic | 3.0 | 4.6 | 3.7 | 4.6 | |
Other Race | 4.7 | 3.5 | 5.6 | 5.4 | |
Educational level | < 0.001 | ||||
Less than high school | 15.2 | 20.1 | 19.4 | 21.0 | |
High school | 21.8 | 26.6 | 21.9 | 28.5 | |
More than high school | 63.0 | 53.3 | 58.7 | 50.5 | |
Marital status | < 0.001 | ||||
Married/ Living with partner | 69.0 | 66.2 | 68.5 | 72.0 | |
Widowed/Divorced/ Separated | 21.4 | 25.5 | 23.2 | 21.1 | |
Never married | 9.6 | 8.4 | 8.3 | 6.9 | |
PIR | 2.64 ± 1.66 | 2.49 ± 1.63 | 2.59 ± 1.66 | 2.30 ± 1.55 | < 0.001 |
BMI (kg/m2) | 26.45 ± 5.67 | 27.80 ± 5.41 | 29.06 ± 6.07 | 30.56 ± 5.58 | < 0.001 |
Current smoking | < 0.001 | ||||
Yes | 33.8 | 37.0 | 35.3 | 37.0 | |
NO | 66.2 | 63.0 | 64.7 | 63.0 | |
Comorbidities | |||||
Hypertension (%) | < 0.001 | ||||
Yes | 38.3 | 42.4 | 46.1 | 58.0 | |
NO | 61.7 | 57.6 | 53.9 | 42.0 | |
Diabetes (%) | < 0.001 | ||||
Yes | 5.3 | 8.1 | 13.8 | 29.4 | |
NO | 94.7 | 91.9 | 86.2 | 70.66 | |
Congestive heart failure | < 0.001 | ||||
Yes | 4.3 | 2.0 | 3.9 | 6.2 | |
NO | 95.7 | 98.0 | 96.1 | 93.8 | |
Coronary heart disease | < 0.001 | ||||
Yes | 8.4 | 8.8 | 10.8 | 13.7 | |
NO | 91.6 | 91.2 | 89.2 | 86.3 | |
Stroke | < 0.001 | ||||
Yes | 6.1 | 3.6 | 3.5 | 5.5 | |
NO | 93.9 | 96.4 | 96.5 | 94.5 | |
Laboratory measurements | |||||
Albumin (g/L) | 42.42 ± 2.98 | 42.10 ± 3.05 | 42.25 ± 3.18 | 42.55 ± 3.25 | < 0.001 |
ALT (U/L) | 23.13 ± 22.48 | 24.85 ± 16.21 | 26.58 ± 13.98 | 29.65 ± 17.23 | < 0.001 |
AST (U/L) | 26.19 ± 29.60 | 25.76 ± 16.22 | 27.39 ± 21.87 | 27.41 ± 14.82 | < 0.001 |
ALP (U/L) | 64.51 ± 21.04 | 68.00 ± 19.80 | 70.69 ± 25.21 | 72.28 ± 24.18 | < 0.001 |
GGT(U/L) | 23.09 ± 23.58 | 28.04 ± 34.32 | 33.72 ± 34.85 | 44.16 ± 57.80 | < 0.001 |
Total bilirubin (umol/L) | 11.89 ± 4.91 | 12.00 ± 5.26 | 12.08 ± 4.94 | 12.15 ± 4.80 | < 0.001 |
BUN (mmol/L) | 4.97 ± 1.83 | 4.74 ± 1.67 | 4.89 ± 1.97 | 5.18 ± 2.03 | < 0.001 |
Creatinine (umol/L) | 77.57 ± 36.10 | 76.14 ± 21.74 | 79.99 ± 20.43 | 80.29 ± 30.87 | < 0.001 |
Uric acid (umol/L) | 305.57 ± 77.65 | 321.51 ± 82.03 | 351.71 ± 85.30 | 363.42 ± 83.16 | < 0.001 |
Total calcium (mmol/L) | 2.33 ± 0.09 | 2.33 ± 0.09 | 2.34 ± 0.09 | 2.36 ± 0.09 | < 0.001 |
Phosphorus (mmol/L) | 1.18 ± 0.17 | 1.18 ± 0.17 | 1.16 ± 0.17 | 1.18 ± 0.19 | < 0.001 |
Sodium (mmol/L) | 139.41 ± 2.32 | 139.36 ± 2.09 | 139.20 ± 2.28 | 138.75 ± 2.31 | < 0.001 |
Potassium (mmol/L) | 4.09 ± 0.35 | 4.05 ± 0.33 | 4.08 ± 0.35 | 4.10 ± 0.35 | < 0.001 |
Chloride (mmol/L) | 104.19 ± 3.15 | 104.05 ± 2.66 | 103.85 ± 3.06 | 103.13 ± 2.90 | < 0.001 |
FG (mmol/L) | 5.49 ± 0.79 | 5.68 ± 0.65 | 6.06 ± 1.13 | 7.19 ± 2.67 | < 0.001 |
TC (mmol/L) | 4.85 ± 0.96 | 5.09 ± 0.99 | 5.26 ± 1.17 | 5.47 ± 1.21 | < 0.001 |
Triglyceride(mmol/L) | 0.71 ± 0.17 | 1.11 ± 0.17 | 1.57 ± 0.28 | 2.58 ± 0.70 | < 0.001 |
HDL-C (mmol/L) | 1.69 ± 0.56 | 1.47 ± 0.41 | 1.30 ± 0.34 | 1.12 ± 0.27 | < 0.001 |
LDL-C (mmol/L) | 2.83 ± 0.78 | 3.11 ± 0.88 | 3.23 ± 1.06 | 3.17 ± 1.11 | < 0.001 |
α-Klotho (pg/mL) | 849.68 ± 366.15 | 833.98 ± 289.27 | 809.10 ± 268.28 | 804.09 ± 283.65 | < 0.001 |