From: The role of incretins in gestational diabetes: a case-control study on the impact of obesity
 | Obese GDM n:24 | Non-Obese GDM n:24 | Obese Non-GDM n:24 | Non-Obese Non-GDM n:24 | P |
---|---|---|---|---|---|
Age (years) | 30.8 ± 4.8 | 30 ± 5.7 | 27 ± 5.0 | 28.3 ± 4.4 | 0.097 |
Smoking | 1 (4.2) | 1 (4.2) | 3 (12.5) | 1 (4.2) | 0.708 |
Gestational age (weeks) | 27 (24–28) | 27 (24–28) | 26 (24–28) | 26 (24–28) | 0.238 |
Height (cm) | 161 ± 7.6 | 161.5 ± 5 | 160.7 ± 6.4 | 161.0 ± 6.2 | 0.95 |
Weight (kg) | 94 ± 13 | 72 ± 7.3 | 89 ± 12 | 67.3 ± 8.5 | < 0.001 |
Body Mass Index (kg/m2) | 35.9 ± 3.7 | 27.5 ± 1.8 | 34.7 ± 3.7 | 25.9 ± 2.2 | < 0.001 |
Gestational Weight Gain (kg) | 8.9 ± 4.4 | 7.3 ± 3.9 | 8 ± 4.6 | 6.3 ± 3.4 | 0.215 |
Gravidity | 3. (0–9) | 2 (1–3) | 2 (1–3) | 2 (1–5) | 0.094 |
Parity | 1 (0–3) | 1 (0–2) | 0 (0–2) | 0 (0–5) | 0.100 |
Live-birth | 1 (0–3) | 1 (0–2) | 0 (0–2) | 0 (0–2) | 0.058 |
Miscarriage | 0 (0–5) | 0 (0–1) | 0 (0–1) | 0 (0–2) | 0.053 |
Systolic Blood Pressure (mmHg) | 109.2 ± 5.9 | 108.9 ± 8.6 | 108.7 ± 8.6 | 105 ± 7.1 | 0.255 |
Diastolic Blood Pressure (mmHg) | 71 ± 5.7 | 67 ± 7.9 | 68.4 ± 7.0 | 64 ± 7.7 | 0,014 |
Glucose fasting (mg/dL) | 99 ± 13 | 92.4 ± 13.6 | 79.9 ± 5.4 | 78.2 ± 6.1 | < 0.001 |
Glucose 1st hour (mg/dL) | 198.9 ± 41 | 184.5 ± 48 | 128.2 ± 25 | 127.7 ± 25.9 | < 0.001 |
Glucose 2nd hour (mg/dL) | 144.9 ± 52.9 | 147.6 ± 44.1 | 105 ± 21.9 | 100.9 ± 26.9 | < 0.001 |
GLP-1 (ng/mL) | 908 (330–1053) | 805 (282–908) | 739 (315–938) | 731 (460–962) | < 0.001 |
GLP-2 (ng/mL) | 839 (361–1178) | 855 (668–988) | 869 (561–1178) | 877 (743–1065) | 0.325 |
GIP (ng/mL) | 866 (562–1468) | 870 (811–988) | 906 (801–1178) | 914 (736–1216) | 0.595 |