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Table 2 Effect of green coffee supplementation on body weight, BMI, WC, blood pressure, lipid profile and miRNAs

From: Effect of green coffee on miR-133a, miR-155 and inflammatory biomarkers in obese individuals

 

Control group (n = 80)

Coffee green group (n = 80)

 

Baseline

After 6 months

Pa value

Baseline

After 6 months

Pa

Pb baseline

Pc after

Body weight (Kg)

90.81 ± 15.45

89.29 ± 14.43

0.000

93.60 ± 11.00

84.36 ± 10.09

0.000

0.191

0.013

BMI (kg/m2)

30.93 ± 4.57

30.42 ± 4.27

0.000

31.59 ± 3.61

28.49 ± 3.48

0.000

0.315

0.002

wC (cm)

105.92 ± 11.30

101.53 ± 10.79

0.000

104.59 ± 13.32

97.41 ± 13.85

0.000

0.497

0.038

Systolic BP (mmHg)

138.25 ± 12.47

129.50 ± 6.36

0.000

137.64 ± 13.94

126.20 ± 8.04

0.000

0.770

0.005

Diastolic BP (mmHg)

87.44 ± 3.38

83.93 ± 3.62

0.000

86.65 ± 2.54

81.66 ± 4.45

0.000

0.098

0.001

TC (mg/dL)

211.89 ± 24.80

199.04 ± 31.89

0.000

215.04 ± 32.95

182.24 ± 23.9

0.000

0.495

0.000

LDL-C (mg/dL)

137.99 ± 24.99

128.33 ± 31.08

0.000

141.12 ± 33.05

114.42 ± 22.58

0.000

0.499

0.001

HDL-C (mg/dL)

42.11 ± 2.60

41.54 ± 4.56

0.229

41.54 ± 2.41

43.10 ± 2.44

0.000

0.149

0.008

TG (mg/dL)

158.93 ± 9.07

145.90 ± 24.30

0.000

161.89 ± 14.03

123.59 ± 22.44

0.000

0.115

0.002

miR-133a (RCN)

0.91 (0.14–2.01)

0.90 (0.20–1.50)

0.000

0.94 (0.34–2.59)

0.67 (0.27–1.40)

0.000

0.384

0.001

miR-155 (RCN)

1.24 (0.20–3.78)

1.20 (0.22–3.40)

0.090

1.14 (0.33–3.65)

1.10 (0.30–3.40)

0.000

0.375

0.218

  1. Values shown are means ± S.D or median (Min–Max)
  2. P < 0.05 was set as significant
  3. P values are in italics
  4. BMI body mass index = weight (kg)/height (m2), WC waist circumference (cm), TG Triglycerides, TC total cholesterol, LDL-C: low density lipoprotein-cholesterol, HDL-C: high density lipoprotein-cholesterol. RCN: relative copy Number, Green coffee bean extract (800 mg) was given daily for 6 months. Pa Paired T test or Wilcoxon Signed Ranks Test, Pb Independent T test or Mann–Whitney U baseline, Pc Independent T test or Mann–Whitney U after intervention