The independent association between 25 (OH) vitamin D deficiency, HOMA-IR, and lipid profile with APOE genotyping in obese cases with and without T2DM

Table 1 Demographic and biochemical data and for all cases

Parameter	Mean (µ ± SD), n%			P-value
Parameter	Control group. N = 100	Obese cases N = 100	Obese cases with T2DM N = 100	Control Vs Obese cases	Control Vs Obese cases with T2DM	Obese cases Vs Obese cases with T2DM
Sex	Male (29) 29% Female (71) 71%	Male (31) 31% Female (69) 69%	Male (38) 38% Female (62) 62%
Age	42.7 ± 3.7	43.2 ± 4.6	42.8 ± 5.4	0.397	0.813	0.626
BMI	24.6 ± 2.2	35.6 ± 4.7	32.85 ± 3.4	< 0.001	< 0.001	< 0.001
25(OH) vitamin D	25.2 ± 3.1	10.1 ± 4.9	10.2 ± 4.3	< 0.001	< 0.001	0.868
FBS (mg/dl)	85.7 ± 9.3	105.6 ± 20.2	131.3 ± 40.6	< 0.001	< 0.001	< 0.001
HbA1C %	4.7 ± 0.42	5.5 ± 0.7	7.8 ± 1.2	< 0.001	< 0.001	< 0.001
Fasting insulin mU/L	5.4 ± 3.4	7 ± 4.8	8.2 ± 3.6	0.007	< 0.001	0.046
HOMA-IR	1.1 ± 0.7	1.8 ± 1.3	2.6 ± 1.74	< 0.001	< 0.001	0.002
TC (mg/dl)	152.5 ± 28.2	183.8 ± 38.5	181.2 ± 40.1	< 0.001	< 0.001	0.632
TG (mg/dl)	129 ± 33.7	164.1 ± 62.7	148.7 ± 51	< 0.001	0.002	0.059
HDL-C (mg/dl)	55.9 ± 10.2	55.5 ± 8.6	50.1 ± 9.1	0.757	< 0.001	< 0.001
LDL-C (mg/dl)	70. ± 25.337	95.5 ± 33	101.3 ± 37.6	< 0.001	< 0.001	0.248
TG/HDL-C ratio	1.96 ± 0.721	3.05 ± 1.3	3.1 ± 1.3	< 0.001	< 0.001	0.729

ISSN: 1758-5996