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Table 6 Subgroup analysis of 365-day mortality among patients

From: Independent effects of the glucose-to-glycated hemoglobin ratio on mortality in critically ill patients with atrial fibrillation

Subgroup

Variable

Total

Event (%)

HR (95CI)

P value

P for interaction

Age

     

0.548

  < 65

Tertile1

233

37 (15.9)

1.45 (0.84 ~ 2.51)

0.187

 

Tertile2

233

21 (9)

1(Ref)

  

Tertile3

239

27 (11.3)

1.62 (0.9 ~ 2.94)

0.11

 

Trend test

705

85 (12.1)

1.03 (0.78 ~ 1.36)

0.819

 

  ≥ 65

Tertile1

857

239 (27.9)

1.35 (1.1 ~ 1.66)

0.004

 

Tertile2

866

157 (18.1)

1(Ref)

  

Tertile3

857

222 (25.9)

1.72 (1.4 ~ 2.12)

 < 0.001

 

Trend test

2580

618 (24)

1.13 (1.02 ~ 1.25)

0.022

 

Gender

     

0.795

 Female

Tertile1

457

136 (29.8)

1.29 (0.98 ~ 1.69)

0.068

 

Tertile2

424

92 (21.7)

1(Ref)

  

Tertile3

407

124 (30.5)

1.68 (1.28 ~ 2.21)

 < 0.001

 

Trend test

1288

352 (27.3)

1.14 (0.99 ~ 1.3)

0.061

 

 Male

Tertile1

633

140 (22.1)

1.48 (1.13 ~ 1.95)

0.005

 

Tertile2

675

86 (12.7)

1(Ref)

  

Tertile3

689

125 (18.1)

1.82 (1.38 ~ 2.41)

 < 0.001

 

Trend test

1997

351 (17.6)

1.1 (0.96 ~ 1.26)

0.169

 

Race

     

0.784

 White

Tertile1

692

184 (26.6)

1.51 (1.19 ~ 1.9)

0.001

 

Tertile2

765

120 (15.7)

1(Ref)

  

Tertile3

728

148 (20.3)

1.58 (1.24 ~ 2.02)

 < 0.001

 

Trend test

2185

452 (20.7)

1.01 (0.89 ~ 1.14)

0.895

 

 Black

Tertile1

61

18 (29.5)

1.4 (0.57 ~ 3.43)

0.465

 

Tertile2

47

8 (17)

1(Ref)

  

Tertile3

41

18 (43.9)

2.91 (1.17 ~ 7.22)

0.021

 

Trend test

149

44 (29.5)

1.44 (0.98 ~ 2.1)

0.062

 

 Other

Tertile1

337

74 (22)

1.08 (0.75 ~ 1.57)

0.675

 

Tertile2

287

50 (17.4)

1(Ref)

  

Tertile3

327

83 (25.4)

1.71 (1.19 ~ 2.45)

0.004

 

Trend test

951

207 (21.8)

1.26 (1.07 ~ 1.5)

0.007

 

BMI

     

0.481

  ≤ 24.9

Tertile1

275

96 (34.9)

1.45 (1.03 ~ 2.02)

0.031

 

Tertile2

259

58 (22.4)

1(Ref)

  

Tertile3

215

64 (29.8)

1.61 (1.11 ~ 2.32)

0.011

 

Trend test

749

218 (29.1)

1.02 (0.86 ~ 1.22)

0.789

 

 25–30

Tertile1

347

83 (23.9)

1.44 (1.01 ~ 2.04)

0.041

 

Tertile2

376

56 (14.9)

1(Ref)

  

Tertile3

373

76 (20.4)

1.75 (1.23 ~ 2.5)

0.002

 

Trend test

1096

215 (19.6)

1.1 (0.92 ~ 1.31)

0.294

 

  > 30

Tertile1

468

97 (20.7)

1.2 (0.86 ~ 1.66)

0.282

 

Tertile2

464

64 (13.8)

1(Ref)

  

Tertile3

508

109 (21.5)

1.76 (1.29 ~ 2.41)

 < 0.001

 

Trend test

1440

270 (18.8)

1.23 (1.05 ~ 1.43)

0.008

 

Hypertension

     

0.3

 No

Tertile1

614

181 (29.5)

1.29 (1.01 ~ 1.65)

0.041

 

Tertile2

519

106 (20.4)

1(Ref)

  

Tertile3

495

128 (25.9)

1.52 (1.17 ~ 1.98)

0.002

 

Trend test

1628

415 (25.5)

1.07 (0.94 ~ 1.21)

0.301

 

 Yes

Tertile1

476

95 (20)

1.45 (1.06 ~ 1.98)

0.022

 

Tertile2

580

72 (12.4)

1(Ref)

  

Tertile3

601

121 (20.1)

1.85 (1.38 ~ 2.49)

 < 0.001

 

Trend test

1657

288 (17.4)

1.16 (1 ~ 1.35)

0.056

 

Heart failure

     

0.947

 No

Tertile1

522

120 (23)

1.51 (1.12 ~ 2.02)

0.006

 

Tertile2

637

78 (12.2)

1(Ref)

  

Tertile3

698

133 (19.1)

1.75 (1.31 ~ 2.33)

 < 0.001

 

Trend test

1857

331 (17.8)

1.09 (0.95 ~ 1.25)

0.237

 

 Yes

Tertile1

568

156 (27.5)

1.22 (0.95 ~ 1.57)

0.127

 

Tertile2

462

100 (21.6)

1(Ref)

  

Tertile3

398

116 (29.1)

1.67 (1.27 ~ 2.19)

 < 0.001

 

Trend test

1428

372 (26.1)

1.15 (1.01 ~ 1.31)

0.035

 

Cancer

     

0.515

 No

Tertile1

894

207 (23.2)

1.23 (0.98 ~ 1.54)

0.069

 

Tertile2

901

136 (15.1)

1(Ref)

  

Tertile3

938

209 (22.3)

1.73 (1.39 ~ 2.15)

 < 0.001

 

Trend test

2733

552 (20.2)

1.19 (1.07 ~ 1.33)

0.001

 

 Yes

Tertile1

196

69 (35.2)

1.85 (1.25 ~ 2.75)

0.002

 

Tertile2

198

42 (21.2)

1(Ref)

  

Tertile3

158

40 (25.3)

1.49 (0.95 ~ 2.33)

0.083

 

Trend test

552

151 (27.4)

0.85 (0.68 ~ 1.05)

0.137

 

CKD

     

0.516

 No

Tertile1

769

171 (22.2)

1.55 (1.23 ~ 1.97)

 < 0.001

 

Tertile2

898

119 (13.3)

1(Ref)

  

Tertile3

910

180 (19.8)

1.84 (1.45 ~ 2.32)

 < 0.001

 

Trend test

2577

470 (18.2)

1.09 (0.97 ~ 1.23)

0.145

 

 Yes

Tertile1

321

105 (32.7)

1.09 (0.79 ~ 1.52)

0.587

 

Tertile2

201

59 (29.4)

1(Ref)

  

Tertile3

186

69 (37.1)

1.45 (1.01 ~ 2.08)

0.043

 

Trend test

708

233 (32.9)

1.13 (0.96 ~ 1.33)

0.131

 

AKI

     

0.403

 No

Tertile1

663

129 (19.5)

1.43 (1.09 ~ 1.86)

0.01

 

Tertile2

809

100 (12.4)

1(Ref)

  

Tertile3

869

155 (17.8)

1.59 (1.24 ~ 2.05)

 < 0.001

 

Trend test

2341

384 (16.4)

1.08 (0.95 ~ 1.22)

0.269

 

 Yes

Tertile1

427

147 (34.4)

1.35 (1.02 ~ 1.79)

0.036

 

Tertile2

290

78 (26.9)

1(Ref)

  

Tertile3

227

94 (41.4)

2 (1.47 ~ 2.72)

 < 0.001

 

Trend test

944

319 (33.8)

1.17 (1.02 ~ 1.35)

0.027

 

Stroke

     

0.951

 No

Tertile1

954

226 (23.7)

1.34 (1.08 ~ 1.67)

0.008

 

Tertile2

915

136 (14.9)

1(Ref)

  

Tertile3

920

192 (20.9)

1.7 (1.36 ~ 2.12)

 < 0.001

 

Trend test

2789

554 (19.9)

1.11 (1 ~ 1.24)

0.045

 

 Yes

Tertile1

136

50 (36.8)

1.52 (0.99 ~ 2.33)

0.054

 

Tertile2

184

42 (22.8)

1(Ref)

  

Tertile3

176

57 (32.4)

1.84 (1.21 ~ 2.81)

0.004

 

Trend test

496

149 (30)

1.11 (0.89 ~ 1.38)

0.359

 
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Diabetology & Metabolic Syndrome

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