Table 1 Patients' baseline information
Characteristic | Total (n = 3285) | Tertile1 (n = 1099) | Tertile2 (n = 1090) | Tertile3 (n = 1096) | P-value |
|---|---|---|---|---|---|
Age (years) | 0.939 | ||||
< 65 | 705 (21.46) | 233 (21.20) | 233 (21.38) | 239 (21.81) | |
≥ 65 | 2580 (78.54) | 866 (78.80) | 857 (78.62) | 857 (78.19) | |
Gender (%) | 0.068 | ||||
Male | 1288 (39.21) | 460 (41.86) | 421 (38.62) | 407 (37.14) | |
Female | 1997 (60.79) | 639 (58.14) | 669 (61.38) | 689 (62.86) | |
Race, n (%) | 0.010 | ||||
White | 2185 (66.51) | 696 (63.33) | 761 (69.82) | 728 (66.42) | |
Black | 149 (4.54) | 61 (5.55) | 47 (4.31) | 41 (3.74) | |
Other | 951 (28.95) | 342 (31.12) | 282 (25.87) | 327 (29.84) | |
BMI, kg/m2, n (%) | 0.023 | ||||
≤ 24.9 | 749 (22.8) | 277 (25.2) | 257 (23.6) | 215 (19.6) | |
25–30 | 1096 (33.4) | 351 (31.9) | 372 (34.1) | 373 (34) | |
> 30 | 1440 (43.8) | 471 (42.9) | 461 (42.3) | 508 (46.4) | |
Hypertension, n (%) | < 0.001 | ||||
No | 1628 (49.56) | 620 (56.41) | 513 (47.06) | 495 (45.16) | |
Yes | 1657 (50.44) | 479 (43.59) | 577 (52.94) | 601 (54.84) | |
Diabetes, n (%) | < 0.001 | ||||
No | 2141 (65.18) | 492 (44.77) | 830 (76.15) | 819 (74.73) | |
Yes | 1144 (34.82) | 607 (55.23) | 260 (23.85) | 277 (25.27) | |
Heart failure, n (%) | < 0.001 | ||||
No | 1857 (56.53) | 523 (47.59) | 636 (58.35) | 698 (63.69) | |
Yes | 1428 (43.47) | 576 (52.41) | 454 (41.65) | 398 (36.31) | |
AMI, n (%) | 0.016 | ||||
No | 2813 (85.63) | 916 (83.35) | 955 (87.61) | 942 (85.95) | |
Yes | 472 (14.37) | 183 (16.65) | 135 (12.39) | 154 (14.05) | |
Cancer, n (%) | 0.035 | ||||
No | 2733 (83.20) | 902 (82.07) | 893 (81.93) | 938 (85.58) | |
Yes | 552 (16.80) | 197 (17.93) | 197 (18.07) | 158 (14.42) | |
CKD, n (%) | < 0.001 | ||||
No | 2577 (78.45) | 774 (70.43) | 893 (81.93) | 910 (83.03) | |
Yes | 708 (21.55) | 325 (29.57) | 197 (18.07) | 186 (16.97) | |
AKI, n (%) | < 0.001 | ||||
No | 2341 (71.26) | 668 (60.78) | 804 (73.76) | 869 (79.29) | |
Yes | 944 (28.74) | 431 (39.22) | 286 (26.24) | 227 (20.71) | |
Stroke, n (%) | 0.007 | ||||
No | 2789 (84.90) | 963 (87.63) | 906 (83.12) | 920 (83.94) | |
Yes | 496 (15.10) | 136 (12.37) | 184 (16.88) | 176 (16.06) | |
Hyperlipidemia, n (%) | 0.960 | ||||
No | 1494 (45.48) | 496 (45.13) | 498 (45.69) | 500 (45.62) | |
Yes | 1791 (54.52) | 603 (54.87) | 592 (54.31) | 596 (54.38) | |
HbA1c, %, M (Q₁, Q₃) | 5.90 (5.50, 6.50) | 6.40 (5.90,7.50) | 5.80 (5.50,6.10) | 5.70 (5.30,6.10) | < 0.001 |
Glugose, (mmol/L), M (Q₁, Q₃) | 90.00 (80.00, 100.00) | 75.00 (65.00,84.00) | 89.00 (84.00,95.00) | 102.00 (95.00,115.00) | < 0.001 |
WBC (× 109/L), M (Q₁, Q₃) | 11.10 (8.20, 14.90) | 11.40 (8.20,15.40) | 11.10 (8.20,14.80) | 11.05 (8.30,14.60) | 0.475 |
HGB(g/L), M (Q₁, Q₃) | 104.0 (88.0, 122.0) | 98.0 (85.0,116.0) | 104.0 (88.0,122.0) | 109.0 (91.0,126.0) | < 0.001 |
Creatinine, (mg/dL) M (Q₁, Q₃) | 1.00 (0.80, 1.30) | 1.00 (0.80,1.45) | 0.90 (0.70,1.20) | 0.90 (0.70,1.20) | < 0.001 |
serum lactate, (mmol/L) M (Q₁, Q₃) | 1.8 (1.3, 2.6) | 1.9 (1.3, 2.7) | 1.8 (1.3, 2.7) | 1.8 (1.3, 2.5) | 0.048 |
INR, M (Q₁, Q₃) | 1.40 (1.20, 1.60) | 1.40 (1.20,1.60) | 1.40 (1.20,1.60) | 1.30 (1.20,1.50) | < 0.001 |
SOFA, M (Q₁, Q₃) | 5.00 (3.00, 7.00) | 5.00 (3.00,8.00) | 4.00 (2.00,7.00) | 4.00 (2.00,6.00) | < 0.001 |
OASIS, M (Q₁, Q₃) | 32.00 (27.00, 37.00) | 33.00 (27.00,39.00) | 31.00 (27.00,37.00) | 31.00 (26.00,37.00) | < 0.001 |
30-day mortality, n (%) | 344 (10.47) | 116 (10.56) | 69 (6.33) | 159 (14.51) | < 0.001 |
90-day mortality, n (%) | 494 (15.04) | 188 (17.11) | 110 (10.09) | 196 (17.88) | < 0.001 |
365-day mortality, n (%) | 703 (21.40) | 278 (25.30) | 176 (16.15) | 249 (22.72) | < 0.001 |