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Table 1 Demographic and baseline laboratory data of the studied patients

From: Association between bone turnover markers, bone mineral density, and serum osteoglycine in middle-aged men with Type 2 Diabetes mellitus

Variables

Diabetic Group (n = 78)

Control Group (n = 13)

P-Value

Age (Years) (Mean ± SD)

55.78 ± 7.36

48.8 ± 5.48

0.0016

Duration of Diabetes (Years) (Mean ± SD)

10.77 ± 9.02

0

-

BMI (kg/m²) (Mean ± SD)

30.24 ± 5.05

26.7 ± 3.7

0.0177

Waist circumference (cm) (Mean ± SD)

105.35 ± 14.98

96.3 ± 12.8

0.0429

Smokers (Number (%))

40 (51.3)

11 (84.6)

0.0259

Hypertension (Number (%))

20 (25.6)

3 (23.1)

0.8485

Heart Disease (Number (%))

12 (15.4)

0 (0)

-

Oral Treatment only (Number (%))

38 (48.7)

0 (0)

-

Insulin Treatment only (Number (%))

15 (19.2)

0 (0)

-

Oral and Insulin Treatment (Number (%))

24 (30.8)

0 (0)

-

HbA1c (Mean ± SD)

8.4 ± 1.6

5.4 ± 0.2

0.000

HOMA-IR (U/ml) (Mean ± SD)

2.8 ± 3.8

1.5 ± 0.99

0.214

Vitamin D (ng/ml) (Mean ± SD)

15.3 ± 8.3

28.5 ± 20.02

0.037

PTH (pg/ml) (Mean ± SD)

56.7 ± 24.6

47.5 ± 15.55

0.196

CTX (ng/ml) (Mean ± SD)

5.3 ± 5.2

2.8 ± 1.01

0.000

P1NP (ng/ml) (Mean ± SD)

157.2 ± 62.4

101.05 ± 70.4

0.004

Osteoglycin (pg/ml) (Mean ± SD)

13.5 ± 6.9

6.06 ± 3.7

0.000

DEXA Lumbar Spine (SD) (Mean ± SD)

-0.38 ± 1.3

-0.98 ± 0.95

0.109

DEXA neck femur (SD) (Mean ± SD)

-0.32 ± 1.4

-0.14 ± 1.4

0.67

DEXA total femur (SD) (Mean ± SD)

0.00 ± 1.3

-0.13 ± 1.5

0.743

  1. BMI = Body mass index; HbA1c = glycated hemoglobin; HOMA IR = Homeostasis Model Assessment of Insulin Resistance; PTH = serum parathyroid hormone; CTX = serum C-terminal telopeptides of type I collagen; P1NP = serum procollagen type 1 N-terminal propeptide; SD = Standard Deviation