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Table 1 Baseline patient characteristics according to SHR levels

From: Association of the stress hyperglycemia ratio with coronary artery disease complexity as assessed by the SYNTAX score in patients with acute coronary syndrome

Variable

Total

n = 4715

Q1 (SHR ≤ 0.68)

n = 942

Q2 (0.68 < SHR ≤ 0.737)

n = 944

Q3 (0.737 < SHR ≤ 0.795)

n = 942

Q4 (0.795 < SHR ≤ 0.875)

n = 944

Q5 (SHR > 0.875)

n = 943

P value

SHR

0.79 ± 0.16

0.62 ± 0.06

0.71 ± 0.02

0.77 ± 0.02

0.83 ± 0.02

1.03 ± 0.18

< 0.001

Age, year

57.88 ± 10.26

58.93 ± 10.53

58.13 ± 10.30

57.82 ± 10.01

57.36 ± 10.12

57.17 ± 10.27

0.002

Male, n (%)

3542 (75.1)

678 (72)

694 (73.5)

708 (75.2)

706 (74.8)

756 (80.2)

< 0.001

BMI, kg/m2

25.83 ± 3.28

25.52 ± 3.49

25.96 ± 3.14

25.75 ± 3.30

25.92 ± 3.20

26.01 ± 3.22

0.006

SBP, mmHg

126.75 ± 16.65

126.02 ± 17.00

126.24 ± 16.62

126.69 ± 16.40

126.57 ± 16.56

128.21 ± 16.59

0.038

DBP, mmHg

77.49 ± 10.63

76.69 ± 10.26

77.58 ± 10.71

78.12 ± 11.07

77.56 ± 10.49

77.49 ± 10.58

0.070

Current smoker, n (%)

2722 (57.7)

526 (55.8)

549 (58.2)

556 (59)

532 (56.4)

559 (59.3)

0.44

DM, n (%)

1909 (40.5)

498 (52.9)

293 (31)

303 (32.2)

319 (33.8)

496 (52.6)

< 0.001

Hypertension, n (%)

2997 (63.6)

602 (63.9)

600 (63.6)

576 (61.1)

609 (64.5)

610 (64.7)

0.508

Dyslipidemia, n (%)

3017 (64.0)

621 (65.9)

609 (64.5)

588 (62.4)

617 (65.4)

582 (61.7)

0.237

Previous MI, n (%)

1671 (35.4)

338 (35.9)

319 (33.8)

304 (32.3)

294 (31.1)

416 (44.1)

< 0.001

Previous stroke, n (%)

523 (11.1)

121 (12.8)

126 (13.3)

78 (8.3)

105 (11.1)

93 (9.9)

0.002

PVD, n (%)

258 (5.5)

57 (6.1)

57 (6)

41 (4.4)

49 (5.2)

54 (5.7)

0.442

COPD, n (%)

112 (2.4)

25 (2.7)

24 (2.5)

24 (2.5)

14 (1.5)

25 (2.7)

0.393

eGFR, mL/min/1.73m2

91.79 ± 14.75

91.28 ± 14.44

91.77 ± 14.84

92.09 ± 14.15

93.28 ± 14.04

90.55 ± 16.08

0.001

LVEF, %

63.16 ± 6.86

63.36 ± 6.83

63.60 ± 6.60

63.51 ± 6.60

63.45 ± 6.56

61.88 ± 7.53

< 0.001

 LVEF < 40%, n (%)

38 (0.8)

7 (0.7)

5 (0.5)

7 (0.7)

6 (0.6)

13 (1.4)

0.267

Clinical presentation

      

< 0.001

 UA, n (%)

3267 (69.3)

667 (70.8)

678 (71.8)

686 (72.8)

682 (72.2)

554 (58.7)

 

 NSTEMI, n (%)

418 (8.9%)

70 (7.4)

88 (9.3)

71 (7.5)

80 (8.5)

109 (11.6)

 

 STEMI, n (%)

1030 (21.8%)

205 (21.8)

178 (18.9)

185 (19.6)

182 (19.3)

280 (29.7)

 

Laboratory data

 TG, mmol/L

1.80 ± 1.04

1.76 ± 1.05

1.73 ± 0.90

1.79 ± 0.97

1.76 ± 0.96

1.93 ± 1.29

< 0.001

 TC, mmol/L

4.26 ± 1.05

4.13 ± 1.00

4.16 ± 1.06

4.28 ± 1.02

4.30 ± 1.05

4.44 ± 1.09

< 0.001

 HDL-C, mmol/L

1.03 ± 0.28

1.00 ± 0.27

1.02 ± 0.27

1.03 ± 0.28

1.05 ± 0.29

1.04 ± 0.28

0.003

 LDL-C, mmol/L

2.55 ± 0.90

2.45 ± 0.83

2.49 ± 0.92

2.56 ± 0.87

2.59 ± 0.91

2.69 ± 0.94

< 0.001

 Lp (a), mg/L

288.62 ± 280.23

299.34 ± 273.11

299.89 ± 290.43

282.96 ± 276.89

273.57 ± 277.85

287.35 ± 282.21

0.197

 Hs-CRP, mg/L

3.62 ± 4.06

3.30 ± 3.66

3.41 ± 3.79

3.30 ± 3.85

3.33 ± 3.83

4.77 ± 4.85

< 0.001

 ALB, g/L

42.63 ± 4.22

41.19 ± 3.81

42.20 ± 3.76

43.02 ± 4.09

43.62 ± 4.21

43.14 ± 4.71

< 0.001

 ABG, mmol/L

6.23 ± 2.16

5.24 ± 1.19

5.43 ± 1.19

5.78 ± 1.24

6.22 ± 1.43

8.49 ± 3.17

< 0.001

 HBA1c, %

6.58 ± 1.25

7.00 ± 1.41

6.43 ± 1.05

6.37 ± 1.01

6.34 ± 1.06

6.76 ± 1.50

< 0.001

 Hemoglobin, %

142.58 ± 15.43

139.61 ± 15.36

141.14 ± 14.76

143.58 ± 15.27

144.24 ± 14.88

144.33 ± 16.31

< 0.001

 Uric acid, mmol/L

340.06 ± 84.88

341.17 ± 84.85

345.57 ± 85.18

342.34 ± 81.94

339.26 ± 83.29

331.96 ± 88.59

0.009

Angiographic characteristics

 LM disease, n (%)

238 (5.0)

53 (5.6)

57 (6)

46 (4.9)

35 (3.7)

47 (5)

0.186

 TVD, n (%)

1810 (38.4)

370 (39.3)

352 (37.3)

376 (39.9)

332 (35.2)

380 (40.3)

0.12

 Long lesion, n (%)

2730 (57.9)

544 (57.7)

539 (57.1)

534 (56.7)

539 (57.1)

574 (60.9)

0.344

 Calcified lesions, n (%)

686 (14.5)

142 (15.1)

137 (14.5)

119 (12.6)

125 (13.2)

163 (17.3)

0.041

 Thrombosis, n (%)

153 (3.2)

21 (2.2)

27 (2.9)

16 (1.7)

26 (2.8)

63 (6.7)

< 0.001

 CTO disease, n (%)

723 (15.6)

144 (15.7)

128 (13.7)

120 (13)

145 (15.7)

186 (20)

< 0.001

 SYNTAX score

11.81 ± 7.73

12.41 ± 8.26

11.61 ± 7.36

11.43 ± 7.25

11.12 ± 7.39

12.47 ± 8.26

< 0.001

 SYNTAX score > 22

503 (10.7)

126 (13.4)

80 (8.5)

76 (8.1)

87 (9.2)

134 (14.2)

< 0.001

  1. Abbreviations: ABG: admission blood glucose; ALB: albumin; BMI: body mass index; COPD: chronic obstructive pulmonary disease; CTO: chronic total occlusion; DBP: diastolic blood pressure; eGFR: estimated glomerular filtration rate; Hs-CRP: high-sensitivity C-reactive protein; HDL-C: high density lipoprotein; LDL-C: low density lipoprotein; LM: left main disease; LVEF: left ventricular ejection fraction; MI: myocardial infarction; MVD: multivessel disease; NSTEMI: non-ST-segment elevation myocardial infarction; PVD: peripheral vascular disease; SBP: systolic blood pressure; STEMI: ST-segment elevation myocardial infarction; TG: triglyceride; TC: total cholesterol; UA: unstable angina; SYNTAX: Synergy between PCI with TAXUS™ and Cardiac Surgery. Data are presented as the mean ± SD; median (IQR) or n (%)
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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