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Table 1 Pleiotropic and heterogeneous trials of causality between serum uric acid levels and the risk of diabetic microvascular complications

From: Causality between serum uric acid and diabetic microvascular complications - a mendelian randomization study

Exprosure

Outcome

Pleiotropy

Heterogeneity

MR‒Egger intercept test

Cochran’s Q test

Intercept

p value

Cochran’s Q

p value

Uric acid

Diabetic nephropathy

0.003

0.448

246.408

0.035

T1DM with renal complications

0.004

0.516

260.005

0.012

T2DM with renal complications

0.012

0.016

255.764

0.019

Diabetic retinopathy

-0.002

0.437

327.399

1.88E-07

T1DM with ophthalmic complications

-0.004

0.328

292.442

8.43E-05

T2DM with ophthalmic complications

-0.001

0.903

262.897

0.007

Diabetic neuropathy

-0.000

0.944

306.230

2.41E-05

T1DM with neurological complications

-0.007

0.370

267.731

0.004

T2DM with neurological complications

0.008

0.220

263.213

0.007

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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