Fig. 7

Targeted Thbs1 pharmacological therapy improves insulin resistance phenotype in GDM mice. A Plasma was extracted from normal, GDM, and LSKL-treated GDM mice, and blood glucose and insulin, leptin, adiponectin and hs-CRP levels were measured by glucose meter and ELISA kit. B HE staining and immunohistochemical detection of adipose tissues from normal, GDM, and LSKL treated mice. C HE staining and immunohistochemical detection of liver tissues from these mice. Statistical data were presented as mean ± standard deviation (SD); ns, no significance; *P < 0.05, **P < 0.01, ***P < 0.001